59 Results for "

kidney tissue

" in MedChemExpress (MCE) Product Catalog:
Products (59)

59 Results for "kidney tissue" in MCE Product Catalog:

4
Fenoldopam mesylate
Fenoldopam mesylate
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4 Cited Publications
Cat. No.: HY-B0735A
CAS No.: 67227-57-0
Synonyms: Fenoldopam methanesulfonate; SKF-82526 mesylate
Target:  

Dopamine Receptor

Research Areas:  

Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer

Fenoldopam (SKF-82526) mesylate is a selective dopamine D1 receptor agonist. Fenoldopam mesylate binds to rat D1B dopamine receptors (Kd = 11 nM) and human D1A receptors (Kd = 17 nM) in COS-7 cell membranes expressing the cloned receptors. Fenoldopam mesylate modulates dopamine receptor expression, induces vasorelaxation in vascular tissues, reverses glomerular hyperfiltration in rat models, increases intracellular cAMP levels, promotes DARPP-32 phosphorylation in small cell lung cancer (SCLC) cells, inhibits cytokine secretion, and downregulates T cell activation markers in activated human T cells. Fenoldopam mesylate can be used for research on hypertension, acute kidney injury, psoriasis, and small cell lung cancer .
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2
Saikosaponin C
Saikosaponin C
0 Images
2 Cited Publications
Cat. No.: HY-N0249
CAS No.: 20736-08-7
Category:  

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