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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
laying hen
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "laying hen" in MCE Product Catalog:
Cat. No.: HY-P990183
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Synonyms: Disodium sulfate, meets analytical specification of Ph. Eur. BP USP
Cat. No.: HY-N3085
CAS No.: 52589-11-4
Category:
Rutaceae Extract Flavanonols Plant Flavonoids Metabolic Disease Phenols Polyphenols Disease Research Fields Phellodendron amurense Rupr. Extract
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Cat. No.: HY-P1833
CAS No.: 117680-39-4
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Cat. No.: HY-P1560
CAS No.: 62982-31-4
Synonyms: Lysozyme C (46-61) (chicken)
Cat. No.: HY-P3604
CAS No.: 91097-16-4
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Cat. No.: HY-P3778
CAS No.: 109024-48-8
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Cat. No.: HY-W108381
CAS No.: 394730-71-3
Pyriprole can be used against cat flea. Pyriprole disrupts the flea life cycle through killing of adult fleas before they lay eggs. Pyriprole has residual effect on debris from dog, which results in a decreased ability of cat flea larvae to complete development to the adult stage .
Cat. No.: HY-P990182
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Cat. No.: HY-144098
CAS No.: 2824131-20-4
HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. HDAC8-IN-2 shows significant killing of the schistosome larvae. HDAC8-IN-2 markedly impairs egg laying of adult worm pairs .
Cat. No.: HY-13766
CAS No.: 179033-51-3
Synonyms: VX-853
Timcodar is a macrolide agent, and studies have shown that during adipogenesis, timcodar can significantly inhibit fat accumulation, with an effect similar to that of rapamycin. However, unlike rapamycin, timcodar does not cause immunosuppression and glucose resistance. In addition, timcodar can effectively inhibit the adipogenic transcriptional regulators PPAR?? and C/EBP??, thereby inhibiting genes involved in fat accumulation. These studies lay the foundation for timcodar as a potential anti-obesity therapy, as obesity is becoming a global epidemic.
Cat. No.: HY-P11557
CAS No.: 2007127-11-7
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Cat. No.: HY-P11558
CAS No.: 2007127-12-8
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Cat. No.: HY-P11559
CAS No.: 2007127-13-9
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Cat. No.: HY-120131
CAS No.: 13067-93-1
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Cyanofenphos is an orally active organophosphate insecticide and brain AChE inhibitor with neurotoxicity. Cyanofenphos induces delayed neurotoxicity such as ataxia and paralysis. Cyanofenphos also causes symptoms including somnolence, reduced feed intake and weight loss in hens. Cyanofenphos has a unique self-antagonistic effect: repeated low-dose pre-treatment not only reduces subsequent acute toxicity, but also exacerbates delayed neurotoxicity and attenuates enzyme inhibition, with the protective effect peaking at 24 h after the last pre-treatment. Cyanofenphos is commonly used in studies related to delayed neurotoxicity .
Cat. No.: HY-L935
1039 compounds
POI (Protein of Interest) refers to the target protein, namely the disease-causing protein or key functional protein that undergoes degradation or functional modulation in molecular glue-mediated processes. The Molecular Glue POI Library consists of a series of fragments that can specifically bind to different types of POIs. As key components of molecular glues, these ligands form stable interactions with target proteins, laying the foundation for molecular glues to induce the interaction between POIs and E3 ubiquitin ligases. The covered POIs include various types such as cancer-associated GSPT1, androgen receptors, and abnormally aggregated proteins linked to neurodegenerative diseases.
This fragment library can be applied to the screening and optimization of targeted protein degraders. By screening ligands with high affinity and strong selectivity for specific POIs from the library, core structures can be identified to develop novel molecular glues. For instance, optimization of ligands targeting GSPT1 has yielded molecular glue degraders with enhanced degradation activity. Since many POIs are difficult to drug due to the lack of traditional small-molecule binding pockets, some ligands in the POI Ligand Library can modulate such POIs by inducing protein-protein interactions, thereby further expanding the scope of drug discovery for undruggable targets.
MCE has compiled a POI Fragment Library comprising thousands of POI fragments with molecular weights ranging from 150 to 400. This compound library can be widely applied in Molecular Glue research and development.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
