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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
limker
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "limker" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-43869
CAS No.: 1703768-74-4
Synonyms: PSMA-617 Ligand-Linker Conjugate
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Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is a complex composed of pharmacophore group Glutamate-urea-Lysine peptide coupling linker, which can be used to synthesize Vipivotide tetraxetan (PSMA-617). Glutamate-urea-Lysine selectively binds to prostate-specific membrane antigen (PSMA) .
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NH2-PEG3-C2-NH-Boc (PROTAC Linker 15) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
Cat. No.: HY-40171
CAS No.: 57260-73-8
Synonyms: PROTAC Linker 22
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NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs .
Synonyms: PROTAC Linker 20
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N3-PEG4-C2-NH2 (PROTAC Linker 20) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . N3-PEG4-C2-NH2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-W017440
CAS No.: 112-27-6
Synonyms: PROTAC Linker 25
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Triethylene glycol (PROTAC Linker 25) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
Synonyms: PROTAC Linker 5
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NH2-PEG3-C1-Boc (PROTAC Linker 5) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
Cat. No.: HY-42637
CAS No.: 172531-37-2
Synonyms: PROTAC Linker 14
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N3-PEG3-CH2COOH (PROTAC Linker 14) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . N3-PEG3-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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NAMPT inhibitor-linker 1 is a agent-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-3 consists of an NAMPT inhibitor-linker 1 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526 cells, with IC50s of <3 pM and 9 pM, respectively.
Cat. No.: HY-W004896
CAS No.: 139115-91-6
Synonyms: PROTAC Linker 11
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Boc-NH-PEG2 (PROTAC Linker 11) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
Cat. No.: HY-W007545
CAS No.: 6338-55-2
Synonyms: PROTAC Linker 35
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NH2-PEG3 (PROTAC Linker 35) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. NH2-PEG3 (PROTAC Linker 35) can be used in the synthesis of the PROTAC (β-NF-JQ1) .
Cat. No.: HY-W025896
CAS No.: 106984-09-2
Synonyms: PROTAC Linker 12
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Boc-NH-PEG4 (PROTAC Linker 12) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
Cat. No.: HY-W004710
CAS No.: 51644-96-3
Synonyms: PROTAC Linker 23
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NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs .
Cat. No.: HY-W008474
CAS No.: 153086-78-3
Synonyms: PROTAC Linker 13
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Boc-NH-PEG2-C2-NH2 (PROTAC Linker 13) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
Synonyms: PROTAC Linker 4
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Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs) .
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NAMPT inhibitor-linker 2 is a agent-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-4 consists of an NAMPT inhibitor-linker 2 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526, with IC50s of <7 pM and 40 pM, respectively.
Cat. No.: HY-W017772
CAS No.: 139115-92-7
Synonyms: PROTAC Linker 10
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Boc-NH-PEG3 (PROTAC Linker 10) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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Bis-NH2-PEG2 (PROTAC Linker 19) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
Synonyms: PROTAC Linker 21
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Phenol-amido-C1-PEG3-N3 (PROTAC Linker 21) is an PEG-based PROTAC linker can be used in the synthesis of PROTACs . Phenol-amido-C1-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-168489
CAS No.: 3039487-10-7
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OBI-992 drug-linker is a drug-linker conjugate composed of the TOP I inhibitor Exatecan (HY-13631) and a linker. OBI-992 drug-linker can be used for the synthesis of the ADC OBI-992 .
Cat. No.: HY-160098
CAS No.: 2566530-81-0
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BCN-linker-DXd 2 is a specialized antibody-drug conjugate (ADC) payload-linker complex carrying a derivative of the cytotoxic agent DXd (HY-13631D). BCN-linker-DXd 2 bears a BCN (bicyclononyne) group for click chemical bioconjugation, and can be used for ADC synthesis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
