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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
long-isoform
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "long-isoform" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P7696
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MUC16; FLJ14303; Mucin 16, Cell Surface Associated; Mucin-16; CA125; CA125 Ovarian Cancer Antigen; CA-125; Mucin-16 Short isoform; Ovarian Cancer-Related Tumor Marker CA125; Mucin-16 long isoform; Ovarian Carcinoma Antigen CA125; MUC-16; Cancer Antigen 12
Species:
Human
Source:
HEK293
2
2 Cited Publications
Target:
Research Areas:
MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 μM .
Cat. No.: HY-175240
Target:
Research Areas:
PROTAC BRD4 Degrader-38 is a BRD4 PROTAC degrader with DC50 values of 86 nM and 106 nM against the short and long isoforms of BRD4, respectively. PROTAC BRD4 Degrader-38 covalently binds to the Cys232 residue of TRIM28 to form a ternary complex containing BRD4, thereby promoting the ubiquitination and degradation of BRD4. PROTAC BRD4 Degrader-38 can be used in the research of acute myeloid leukemia .
Cat. No.: HY-176070
Target:
Research Areas:
HRG038 is a covalent CUL4 DCAF16-base PROTAC-liked BRD4 degrader. HRG038 induces proteasome- and Cullin E3 ligase-dependent degradation, covalently targets cysteine residue C173 on DCAF16 to mediate BRD4 degradation, and induces reduction in BRD3 levels. HRG038 shows selective loss of the short BRD4 isoform over the long isoform in non-cancer cells, degrades both BRD4 isoforms in breast cancer cells, and does not impair cell viability in non-cancer cells. HRG038 can be used for the research of breast cancer .
Cat. No.: HY-P78493
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MUC16; FLJ14303; Mucin 16, Cell Surface Associated; Mucin-16; CA125; CA125 Ovarian Cancer Antigen; CA-125; Mucin-16 Short isoform; Ovarian Cancer-Related Tumor Marker CA125; Mucin-16 long isoform; Ovarian Carcinoma Antigen CA125; MUC-16; Cancer Antigen 12
Species:
Human
Source:
HEK293
Cat. No.: HY-P78178
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MUC16; FLJ14303; Mucin 16, Cell Surface Associated; Mucin-16; CA125; CA125 Ovarian Cancer Antigen; CA-125; Mucin-16 Short isoform; Ovarian Cancer-Related Tumor Marker CA125; Mucin-16 long isoform; Ovarian Carcinoma Antigen CA125; MUC-16; Cancer Antigen 12
Species:
Human
Source:
HEK293
Cat. No.: HY-P700960
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MUC16; FLJ14303; Mucin 16, Cell Surface Associated; Mucin-16; CA125; CA125 Ovarian Cancer Antigen; CA-125; Mucin-16 Short isoform; Ovarian Cancer-Related Tumor Marker CA125; Mucin-16 long isoform; Ovarian Carcinoma Antigen CA125; MUC-16; Cancer Antigen 12
Species:
Human
Source:
HEK293
Cat. No.: HY-P700961
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MUC16; FLJ14303; Mucin 16, Cell Surface Associated; Mucin-16; CA125; CA125 Ovarian Cancer Antigen; CA-125; Mucin-16 Short isoform; Ovarian Cancer-Related Tumor Marker CA125; Mucin-16 long isoform; Ovarian Carcinoma Antigen CA125; MUC-16; Cancer Antigen 12
Species:
Human
Source:
HEK293
Cat. No.: HY-P72347
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MUC16; FLJ14303; Mucin 16, Cell Surface Associated; Mucin-16; CA125; CA125 Ovarian Cancer Antigen; CA-125; Mucin-16 Short isoform; Ovarian Cancer-Related Tumor Marker CA125; Mucin-16 long isoform; Ovarian Carcinoma Antigen CA125; MUC-16; Cancer Antigen 125
Species:
Human
Source:
HEK293
Cat. No.: HY-P704985
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MUC16; FLJ14303; Mucin 16, Cell Surface Associated; Mucin-16; CA125; CA125 Ovarian Cancer Antigen; CA-125; Mucin-16 Short isoform; Ovarian Cancer-Related Tumor Marker CA125; Mucin-16 long isoform; Ovarian Carcinoma Antigen CA125; MUC-16; Cancer Antigen 125
Species:
Human
Source:
HEK293
Cat. No.: HY-P705174
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MUC16; FLJ14303; Mucin 16, Cell Surface Associated; Mucin-16; CA125; CA125 Ovarian Cancer Antigen; CA-125; Mucin-16 Short isoform; Ovarian Cancer-Related Tumor Marker CA125; Mucin-16 long isoform; Ovarian Carcinoma Antigen CA125; MUC-16; Cancer Antigen 125
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P705458
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MUC16; FLJ14303; Mucin 16, Cell Surface Associated; Mucin-16; CA125; CA125 Ovarian Cancer Antigen; CA-125; Mucin-16 Short isoform; Ovarian Cancer-Related Tumor Marker CA125; Mucin-16 long isoform; Ovarian Carcinoma Antigen CA125; MUC-16; Cancer Antigen 12
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
