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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
m-nAChR
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "m-nAChR" in MCE Product Catalog:
Cat. No.: HY-188045
Research Areas:
AS3513678 is a positive allosteric modulator of skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR). AS3513678 promotes acetylcholine (ACh) signaling via m-nAChR, shifts the ACh concentration-response curve to the left, and does not activate the receptor in the absence of ACh. AS3513678 can be used for research on myasthenia gravis and congenital myasthenic syndrome .
Cat. No.: HY-188047
Target:
Research Areas:
AS3580239 is a positive allosteric modulator of skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR). AS3580239 promotes acetylcholine (ACh) signaling via m-nAChR, causing a leftward shift of the ACh concentration-response curve. AS3580239 enhances electrically stimulated isometric contraction of the extensor digitorum longus (EDL) muscle. AS3580239 improves neurotransmission and enhances muscle strength. AS3580239 can be used for research on myasthenia gravis .
Cat. No.: HY-188046
Target:
Research Areas:
AS3566987 is a positive allosteric modulator of the skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR). AS3566987 promotes acetylcholine signaling via the skeletal muscle-type nicotinic acetylcholine receptor, and receptor activation requires the involvement of acetylcholine. AS3566987 can be used in the research of neuromuscular diseases (including myasthenia gravis and congenital myasthenic syndrome) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
