10 Results for "

m6A mRNA

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "m6A mRNA" in MCE Product Catalog:

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2
2 Cited Publications
Cat. No.: HY-137187
CAS No.: 2243736-35-6
Purity:  98.88%
Research Areas:  

Cancer

FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N 6-methyladenosine (m6A) demethylase activity .
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2
2 Cited Publications
Cat. No.: HY-N0086R
CAS No.: 1867-73-8
Synonyms: 6-Methyladenosine (Standard); N-Methyladenosine (Standard)
N6-Methyladenosine (Standard) is the analytical standard of N6-Methyladenosine. This product is intended for research and analytical applications. N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities. In Vitro: N6-methyladenosine (m6A) is selectively recognized by the human YTH domain family 2 (YTHDF2) protein to regulate mRNA degradation. N6-methyladenosine (m6A), a prevalent internal modification in the messenger RNA of all eukaryotes, is post-transcriptionally installed by m6A methyltransferase (e.g., MT-A70) within the consensus sequence of G(m6A)C (70%) or A(m6A)C (30%). N6-methyladenosine (m6A)-containing RNAs are greatly enriched in the YTHDF-bound portion and diminished in the flow-through portion . N6-methyladenosine (m6A), the most abundant internal RNA modification, functions in diverse biological processes, including regulation of embryonic stem cell self-renewal and differentiation. N6-methyladenosine (m6A) is a large protein complex, consisting in part of methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14) catalytic subunits .
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Cat. No.: HY-159604
CAS No.: 295348-36-6
Target:  

METTL3

Research Areas:  

Cancer

METTL3-IN-9 (compound C3) is an inhibitor of methyltransferase-like METTL3, an RNA methyltransferase that catalyzes the N6-methyladenosine (m6A) modification of mRNA in eukaryotic cells .
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Cat. No.: HY-175885
PROTAC FTO degrader 1 is a Fat Mass and Obesity-associated Protein (FTO) PROTAC degrader. PROTAC FTO degrader 1 selectively degrades FTO depending on VHL E3 ligase and ubiquitin-proteasome system. PROTAC FTO degrader 1 can increase m6A modifications on mRNAs associated with ribosome biogenesis and promote their YTHDF2-mediated decay. PROTAC FTO degrader 1 can inhibit cancer cells proliferation and induce apoptosis. PROTAC FTO degrader 1 can be used for the research of cancer, such as acute myeloid leukemia (AML) .
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Cat. No.: HY-185601
Research Areas:  

Others

m7(3'-OMeG)(5')vppp(5')(2'-OMe, m6A)pU triammonium is a cap analog that can be used for the synthesis of mRNA.
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Cat. No.: HY-185603
Research Areas:  

Others

m7G(LNA)(5')ppp(5')(2'OMe, m6A)pG trisodium is a cap analog that can be used for the synthesis of mRNA.
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Cat. No.: HY-185617
Research Areas:  

Others

m7(3'OMeG-LNA)(5')ppp(5')(2'OMe,m6A)pG trisodium is a cap analog that can be used for the synthesis of mRNA.
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Cat. No.: HY-P702912
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: METTL3; Methyltransferase Like 3; Methyltransferase 3, N6-Adenosine-Methyltransferase Complex Catalytic Subunit; HMETTL3; MT-A70; CDNA FLJ58857, Highly Similar To N6-Adenosine-Methyltransferase 70 KDa Subunit; Spo8; CDNA FLJ57780, Highly Similar To N6-Adenosine-Methyltransferase 70 KDa Subunit; m6A; AdoMet-Binding Subunit Of The Human mRNA (N6-Adenosine)-Methyltransferase; N(6)-Adenosine-Methyltransferase Catalytic Subunit METTL3; N6-Adenosine-Methyltransferase Catalytic Subunit; mRNA (2'-O-Methyladenosine-N(6)-)-Methyltransferase; mRNA M(6)A Methyltransferase; N(6)-Adenosine-Methyltransferase 70 KDa Subunit; MTA70; N6-Adenosine-Methyltransferase 70 KDa Subunit; IME4; Methyltransferase-Like Protein 3
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P705470
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: METTL3; Methyltransferase Like 3; Methyltransferase 3, N6-Adenosine-Methyltransferase Complex Catalytic Subunit; HMETTL3; MT-A70; CDNA FLJ58857, Highly Similar To N6-Adenosine-Methyltransferase 70 KDa Subunit; Spo8; CDNA FLJ57780, Highly Similar To N6-Adenosine-Methyltransferase 70 KDa Subunit; m6A; AdoMet-Binding Subunit Of The Human mRNA (N6-Adenosine)-Methyltransferase; N(6)-Adenosine-Methyltransferase Catalytic Subunit METTL3; N6-Adenosine-Methyltransferase Catalytic Subunit; mRNA (2'-O-Methyladenosine-N(6)-)-Methyltransferase; mRNA M(6)A Methyltransferase; N(6)-Adenosine-Methyltransferase 70 KDa Subunit; MTA70; N6-Adenosine-Methyltransferase 70 KDa Subunit; IME4; Methyltransferase-Like Protein 3
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P701888
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FTO; IFEX9; FTO Alpha-Ketoglutarate Dependent Dioxygenase; Intragenic FTO Exon 9 Containing Transcript; U6 Small Nuclear RNA (2'-O-Methyladenosine-N(6)-)-Demethylase FTO; mRNA N(6)-Methyladenine Demethylase; U6 Small Nuclear RNA N(6)-Methyladenosine-Demethylase FTO; Fat Mass And Obesity Associated; mRNA (2'-O-Methyladenosine-N(6)-)-Demethylase FTO; m6A(M)-Demethylase FTO; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; AlkB Homolog 9; mRNA N(6)-Methyladenosine Demethylase FTO; MGC5149; Fat Mass And Obesity-Associated Protein; FTO, Alpha-Ketoglutarate Dependent Dioxygenase; TRNA N1-Methyl Adenine Demethylase FTO; Alpha-Ketoglutarate-Dependent Dioxygenase; KIAA1752; BMIQ14; ALKBH9; GDFD
Species:  
Human
Source:  
E. coli
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