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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
mRNA-LNP
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "mRNA-LNP" in MCE Product Catalog:
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21 Cited Publications
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ALC-0159 presents highly mobile surface PEG chains in a dense brush-like conformation, which can form a hydrophilic barrier, reduce non-specific protein adsorption and macrophage uptake, improve colloidal stability, prolong in vivo circulation time, and affect the cellular uptake of LNPs. ALC-0159 dissociates from the surface of mRNA-LNPs under long-term mechanical oscillation stress, thereby reducing steric hindrance, inducing mRNA-LNP fusion, increasing particle size, and releasing unencapsulated mRNA .
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1 Cited Publications
Cat. No.: HY-153229
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Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing firefly luciferase mRNA. Firefly luciferase mRNA-LNP exhibits a stable nanostructure, in which LNP plays a key role in effectively protecting and transporting mRNA to cells. Luciferase is a bioluminescent reporter gene for gene regulation and functional studies. Firefly Luciferase mRNA-LNP expresses firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Firefly luciferase mRNA-LNP is studied in research for RNA delivery, cell viability, and translation efficiency .
Cat. No.: HY-153235
COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein. COVID-19 Spike Protein undertakes the functions of virus binding with host cell receptors, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design. COVID-19 Spike Protein mRNA-LNP can be used for RNA delivery, vaccine formulation and design targeting SARS-CoV-2 .
Cat. No.: HY-153231A
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eGFP mRNA-LNP (500 ng/μL) is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability .
Cat. No.: HY-188106
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Human IGF1 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating human IGF1 mRNA. Human IGF1 mRNA encapsulates human insulin-like growth factor 1 (IGF1) protein, which is involved in mediating growth and development.
Cat. No.: HY-188105
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Human IL10 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Human IL10 mRNA. Human IL10 mRNA is the messenger ribonucleic acid encoding human IL-10. IL-10 mRNA expression is highly inducible and cell type specific.
Cat. No.: HY-188103
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Human IL4 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Human IL4 mRNA. Human IL4 mRNA encapsulates human interleukin 4 (IL4) protein, a pleiotropic cytokine produced by activated T cells that regulates various T and B cell responses, including cell proliferation, survival, and gene expression.
Cat. No.: HY-188107
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Human CD70 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating human CD70 mRNA. Human CD70 mRNA encapsulates the human CD70 molecule (CD70) protein. CD70 induces co-stimulatory T cell proliferation, enhances the generation of cytolytic T cells, and promotes T cell activation.
Cat. No.: HY-188104
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Human IL2 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Human IL2 mRNA. Human IL2 mRNA encapsulates human interleukin 2 (IL2) protein, which belongs to the interleukin 2 (IL2) cytokine subfamily. IL2 is produced by activated CD4+ and CD8+ T lymphocytes and is essential for the proliferation of T cells and B lymphocytes.
Cat. No.: HY-188110
Cas9-T2A-GFP mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Cas9-T2A-GFP mRNA. Cas9-T2A-GFP mRNA encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and green fluorescent protein (GFP), which can be used for genome engineering experiments.
Cat. No.: HY-P12363A
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Scr-MyomP1 peptide is a scrambled peptide derived from the Myomerger protein. Scr-MyomP1 peptide can be conjugated to the surface of lipid nanoparticles and serves as a negative control to verify whether the skeletal muscle targeting effect of MyomP1-modified LNPs is sequence-dependent. Scr-MyomP1-modified mRNA-LNPs do not exhibit skeletal muscle targeting tropism. Scr-MyomP1 peptide can serve as a scrambled negative control for MyomP1 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
