146 Results for "

marrow cell

" in MedChemExpress (MCE) Product Catalog:
Products (146)

146 Results for "marrow cell" in MCE Product Catalog:

20
Rolipram
Rolipram
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20 Publications Verification
Cat. No.: HY-16900
CAS No.: 61413-54-5
Synonyms: (R,S)-Rolipram; (±)-Rolipram; ZK 62711
Target:  

Bacterial HIV Phosphodiesterase (PDE) Epigenetic Reader Domain Amyloid-β

Research Areas:  

Infection Neurological Disease Cancer

Rolipram is a PDE4 inhibitor, with blood-brain barrier permeability, that reverses β-amyloid-induced learning and memory impairment in rats. Rolipram elevates intracellular cAMP and clevels and regulates the cAMP/CREB signaling pathway, thereby alleviating neuroinflammation and apoptotic responses. Rolipram promotes neuronal differentiation of human bone marrow mesenchymal stem cells and inhibits Methamphetamine- and morphine-induced hyperlocomotion in mice. Rolipram also reduces the viability of glioblastoma stem-like cells and enhances Bevacizumab (HY-P9906)-induced cell death. Rolipram inhibits the expression of proinflammatory cytokines and enhances central noradrenergic transmission. Rolipram is mainly used in studies related to various central nervous system diseases including Alzheimer's disease, major depressive disorder, glioblastoma multiforme, and multiple sclerosis .
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9
Neohesperidin
Neohesperidin
0 Images
9 Cited Publications
Cat. No.: HY-N0101
CAS No.: 13241-33-3
Synonyms: Hesperetin 7-O-neohesperidoside
Category:  

Rutaceae Extract Plants Other Families Extract Flavonoids Flavonones Phenols Polyphenols Disease Research Fields Inflammation/Immunology 500 - Internal Server Error | MedChemExpress

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