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27 Results for "

marrow-derived

" in MedChemExpress (MCE) Product Catalog:

Products (27)

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IFN alpha-IFNAR-IN-1 hydrochloride

26 Publications Verification

Cat. No.: HY-12836A

CAS No.: 2070014-98-9

Purity: 99.76%

Target:

IFNAR

Research Areas:

Inflammation/Immunology

IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3- L-differentiated pDC cultures (BM-pDCs) (IC₅₀=2-8 μM) .

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IFN alpha-IFNAR-IN-1

26 Publications Verification

Cat. No.: HY-12836

CAS No.: 844882-93-5

Target:

IFNAR

Research Areas:

Inflammation/Immunology

IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3- L-differentiated pDC cultures (BM-pDCs) (IC₅₀=2-8 μM) .

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RO5256390

3 Cited Publications

Cat. No.: HY-12700

CAS No.: 1043495-96-0

Purity: 98.75%

Target:

Trace Amine-associated Receptor (TAAR)

Research Areas:

Neurological Disease

RO5256390 is an orally effective trace amine associated receptor 1 (TAAR1) agonist. RO5256390 exhibits pro-cognitive and antidepressant-like properties in rodent and primate models, showing similar brain activation patterns to Olanzapine (HY-14541). RO5256390 blocks compulsive overeating behavior in rats. RO5256390 can inhibit ATP (HY-B2176)-induced TNF secretion in mouse bone marrow-derived macrophages .

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Bropirimine

2 Cited Publications

Cat. No.: HY-W008634

CAS No.: 56741-95-8

Synonyms: U-54461; U-54461S; PNU-54461

Target:

Toll-like Receptor (TLR)

Research Areas:

Cancer

Bropirimine (U-54461; U-54461S; PNU-54461) is an orally active TLR7 agonist. Bropirimine inhibits RANKL-induced osteoclast differentiation of mouse bone marrow-derived macrophages (BMMs). Bropirimine exhibits dose-dependent direct inhibitory effects on colony formation of cultured KK-47 and 724 cells. Bropirimine can be used for the study of cancers and bone metabolic disorders such as osteoporosis .

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