country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

5 Results for "

methuosis

" in MedChemExpress (MCE) Product Catalog:

Products (5)

Sort by :

Categories

By Targets

Products

HZX-02-059

Cat. No.: HY-112440

CAS No.: 2240205-30-3

Purity: 99.40%

Synonyms: methuosis inducer 1

Target:

Microtubule/Tubulin NF-κB MDM-2/p53 PI3K Akt c-Myc mTOR Autophagy

Research Areas:

Cancer

HZX-02-059 is an allosteric inhibitor of PIKFYVE, and a methuosis inducer. HZX-02-059 disrupts the PIKfyve/TFEB axis, suppresses tubulin polymerization, reduces phosphorylated mTOR levels, downregulates p53, PI3K/AKT, c-Myc, and NF-κB pathways. HZX-02-059 induces G₂/M cell cycle arrest, apoptosis, and inhibits cancer cell proliferation. HZX-02-059 can be used for the research of lymphoma, double-hit lymphoma, and B-cell acute lymphoblastic leukemia .

Compare