Target:

Research Areas:

Methyl red is a pH-sensitive acid-base indicator and colorimetric reagent with a pKa of 5.1. Methyl red achieves visual judgment of the titration endpoint through reversible structural changes of protonation (red, pH < 4.4) and deprotonation (yellow, pH > 6.2). Methyl red is widely used in acid-base titration in chemical analysis and buffer pH monitoring in biochemistry .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

2

Glutathione ethyl ester

2 Cited Publications

Cat. No.: HY-134124

CAS No.: 92614-59-0

Purity: 95.8%

Target:

Reactive Oxygen Species (ROS)

Research Areas:

Metabolic Disease

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

1

Polymyxin B1

1 Cited Publications

Cat. No.: HY-A0248A

CAS No.: 4135-11-9

Category:

Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics

Target:

Bacterial

Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

1

Astressin 2B

1 Cited Publications

Cat. No.: HY-P1108

CAS No.: 681260-70-8

Target:

CRFR

Research Areas:

Neurological Disease Inflammation/Immunology

Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

1

Astressin 2B TFA

1 Cited Publications

Cat. No.: HY-P1108A

Target:

CRFR

Research Areas:

Neurological Disease Inflammation/Immunology

Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Rusfertide

Cat. No.: HY-P10272

CAS No.: 1628323-80-7

Synonyms: PTG-300

Target:

Ferroportin

Research Areas:

Others

Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Dabcyl acid

Cat. No.: HY-D1045

CAS No.: 6268-49-1

Synonyms: DABCYL; Para-methyl red

Dabcyl acid (Dabcyl) is a nonfluorescent chromophore and a quencher. Dabcyl acid can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Methyl Orange

Cat. No.: HY-118907

CAS No.: 547-58-0

Purity: 99.41%

Target:

Fluorescent Dye

Research Areas:

Others

Methyl Orange is a soluble azo dye commonly used as an acid-base indicator and for staining cells and tissue sections, as well as for dyeing textiles. Methyl Orange appears red at a pH of 3.1 and changes to bright yellow as the pH increases to 4.4. Methyl Orange (500 mg/L) exhibits cytotoxicity and can cause DNA damage .

Compare

loading...