62 Results for "

mitochondrial integrity

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "mitochondrial integrity" in MCE Product Catalog:

12
ATN-161
ATN-161
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12 Publications Verification
Cat. No.: HY-13535
CAS No.: 262438-43-7
Target:  

Integrin Apoptosis NOD-like Receptor (NLR) p38 MAPK Reactive Oxygen Species (ROS) SARS-CoV

Research Areas:  

Cardiovascular Disease Infection Neurological Disease Cancer

ATN-161 is an antagonist of α5β1 integrin and αvβ3 integrin, as well as an inhibitor of fibrosis, an inhibitor of oxidative stress, a tight junction stabilizer, a mitochondrial integrity protector, an angiogenesis inhibitor and an antiviral agent. ATN-161 inhibits NLRP3, MAPK, and ROS. ATN-161 protects mice from SARS-CoV-2 infection . ATN-161 reduces infarct volume, alleviates edema, decreases immune cell infiltration, reduces the area of choroidal neovascularization lesions, lowers tumor microvessel density and viral load. ATN-161 can be used in research related to ischemic stroke, choroidal neovascularization, breast cancer, coronavirus disease 2019 (COVID-19), and liver metastasis of colorectal cancer .
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6
AP39
AP39
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6 Cited Publications
Cat. No.: HY-126124
CAS No.: 1429061-80-2
Purity:  96.35%
Target:  

Reactive Oxygen Species (ROS)

Research Areas:  

Cardiovascular Disease Neurological Disease

AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H2S) donor. AP39 increases intracellular H2S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research .
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5
Phosphorylethanolamine
Phosphorylethanolamine
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5 Cited Publications
Cat. No.: HY-N5034
CAS No.: 1071-23-4
Synonyms: Monoaminoethyl phosphate; NSC 254167; O-Phosphoethanolamine
Category:  

Natural Products Immune System Disorder Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Phosphorylethanolamine (Monoaminoethyl phosphate) is a membrane phospholipid and an important precursor of Phosphatidylcholine (HY-N18891). It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of Phosphorylethanolamine to Phosphatidylcholine in the liver can improve insulin signaling. Phosphorylethanolamine holds promise for research in the fields of cancer, neurodegenerative disorders, and metabolic diseases .
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3
Atractyloside A
Atractyloside A
0 Images
3 Cited Publications
Cat. No.: HY-N0237
CAS No.: 126054-77-1
Category:  

Terpenoids Sesquiterpenes Other Diseases Plants 500 - Internal Server Error | MedChemExpress

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