510 Results for "

moiety

" in MedChemExpress (MCE) Product Catalog:
Products (510)

510 Results for "moiety" in MCE Product Catalog:

6
DBCO-PEG4-Biotin
DBCO-PEG4-Biotin
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6 Publications Verification
Cat. No.: HY-130809
CAS No.: 1255942-07-4
Purity:  99.40%
Target:  

Biochemical Assay Reagents

Research Areas:  

Cancer

DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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5
NucPE1
NucPE1
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5 Cited Publications
Cat. No.: HY-101859
CAS No.: 1404091-23-1
Purity:  ≥98.0%
Synonyms: Nuc-H2O2 Probe
NucPE1 (Nuc-H2O2 Probe) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.
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5
D-Ribose(mixture of isomers)
D-Ribose(mixture of isomers)
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5 Cited Publications
Cat. No.: HY-W018772
CAS No.: 50-69-1
Category:  

Microorganisms Endogenous metabolite Disease Research Fields Saccharides Cancer

Target:  

Endogenous Metabolite

D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .
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4
Mirvetuximab
Mirvetuximab
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4 Cited Publications
Cat. No.: HY-P99225
CAS No.: 1453084-36-0
Synonyms: M9346A
Target:  

Antifolate ADC Antibodies

Research Areas:  

Cancer

Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .
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4
Mirvetuximab (powder)
Mirvetuximab (powder)
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4 Cited Publications
Cat. No.: HY-P99225A
CAS No.: 1453084-36-0
Synonyms: M9346A (powder)

Target:  

Antifolate ADC Antibodies

Research Areas:  

Cancer

Mirvetuximab (M9346A) (powder) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab (powder) is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .
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4
9-Aminoacridine
9-Aminoacridine
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4 Cited Publications
Cat. No.: HY-B1422
CAS No.: 90-45-9
Synonyms: Aminacrine
9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
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3
Pralidoxime chloride
Pralidoxime chloride
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3 Cited Publications
Cat. No.: HY-B1200
CAS No.: 51-15-0
Synonyms: 2-PAM chloride
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
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3
Mito-apocynin (C11)
Mito-apocynin (C11)
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3 Cited Publications
Cat. No.: HY-135869
CAS No.: 1254044-38-6
Purity:  99.84%
Target:  

Mitochondrial Metabolism

Research Areas:  

Neurological Disease

Mito-apocynin (C11), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C11) selectively targets mitochondria, and shows neuroprotective effect. Mito-apocynin (C11) prevents hyposmia and corrects deficits in motor function .
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3
Tris(3-hydroxypropyltriazolylmethyl)amine
Tris(3-hydroxypropyltriazolylmethyl)amine
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3 Cited Publications
Cat. No.: HY-W021042
CAS No.: 760952-88-3
Synonyms: THPTA
Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA) is an accelerating ligand in the copper-catalyzed azide-alkyne cycloaddition reaction (CuAAC) and protects cells from oxidants generated by copper-catalyzed reduction of oxygen by ascorbate. In addition, Tris(3-hydroxypropyltriazolylmethyl)amine can also protect the histidine moiety of biomolecules in a manner proportional to the ligand concentration .
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2
DUPA(OtBu)-OH
DUPA(OtBu)-OH
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2 Cited Publications
Cat. No.: HY-103591
CAS No.: 1026987-94-9
Purity:  ≥98.0%
Target:  

PSMA

Research Areas:  

Cancer

DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer.
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2
DBCO-amine TFA
DBCO-amine TFA
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2 Cited Publications
Cat. No.: HY-W020546
CAS No.: 2007915-94-6
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

DBCO-amine TFA is a simple building block containing a DBCO moiety and an amine group. Amine is very reactive with NHS ester. DBCO is commonly used for copper-free Click Chemistry reactions.
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2
L-Homopropargylglycine
L-Homopropargylglycine
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2 Cited Publications
Cat. No.: HY-140345
CAS No.: 98891-36-2
Purity:  ≥98.0%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

L-Homopropargylglycine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor .
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2
L-Homopropargylglycine hydrochloride
L-Homopropargylglycine hydrochloride
0 Images
2 Cited Publications
Cat. No.: HY-140345A
CAS No.: 942518-19-6
Purity:  ≥98.0%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor .
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2
Sulfobetaine-14
Sulfobetaine-14
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2 Cited Publications
Cat. No.: HY-W099581
CAS No.: 14933-09-6
Synonyms: SB3-14; DMAPS
Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
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1
AP1867-2-(carboxymethoxy)
AP1867-2-(carboxymethoxy)
0 Images
1 Cited Publications
Cat. No.: HY-114420
CAS No.: 2230613-03-1
Purity:  99.85%
Synonyms: PROTAC FKBP12-binding moiety 2
Target:  

FKBP Ligands for Target Protein for PROTAC

Research Areas:  

Cancer

AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12 F36V-directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules .
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D-Melibiose
D-Melibiose
0 Images
1 Cited Publications
Cat. No.: HY-107824
CAS No.: 585-99-9
Purity:  99.73%
Category:  

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