3 Results for "

morphinan

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "morphinan" in MCE Product Catalog:

Cat. No.: HY-N1356A
CAS No.: 3968-19-2
(R)-Reticuline is a key intermediate and precursor in the biosynthetic pathway of morphinan alkaloids. (R)-Reticuline plays a central role in the metabolism of opium poppy (Papaver somniferum). (R)-Reticuline can either undergo O-methylation catalyzed by PSOMT1, or be converted to (+)-Salutaridine via regioselective and stereoselective oxidative coupling under the action of salutaridine synthase (CYP719B1). (R)-Reticuline serves as a direct precursor for the synthesis of important alkaloids such as morphine, codeine and thebaine .
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Cat. No.: HY-159923
CAS No.: 2131199-52-3
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

BPRMU191 is a μ-opioid receptor (MOR) modulator that converts small-molecule morphinan antagonists into G protein-biased MOR agonists, thereby inducing MOR-dependent activation and analgesic effects. Co-administration of BPRMU191 with morphinan antagonists provides analgesia while reducing side effects such as gastrointestinal dysfunction, antinociceptive tolerance, and dependency-related adverse effects. BPRMU191, in combination with morphinan antagonists, offers a potential strategy for studying severe pain management and G protein-coupled receptor modulation .
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Cat. No.: HY-E71139
Research Areas:  

Others

1,2-Dehydroreticulinium reductase (NADPH) (EC 1.5.1.27) reduces the 1,2-Dehydroreticulinium ion to (R)-reticuline, which is a direct precursor of morphinan alkaloids in the poppy plant.
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