199 Results for "

mouse livers

" in MedChemExpress (MCE) Product Catalog:
Products (199)

199 Results for "mouse livers" in MCE Product Catalog:

12
Oil Red O
Oil Red O
0 Images
12 Publications Verification
Cat. No.: HY-D1168
CAS No.: 1320-06-5
Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses .
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8
Dexamethasone acetate
Dexamethasone acetate
0 Images
8 Cited Publications
Cat. No.: HY-14648A
CAS No.: 1177-87-3
Purity:  99.84%
Synonyms: Dexamethasone 21-acetate; Hexadecadrol acetate
Target:  

Glucocorticoid Receptor

Research Areas:  

Inflammation/Immunology

Dexamethasone acetate (Dexamethasone 21-acetate) is the acetate form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone acetate has a longer duration of action than Dexamethasone. Dexamethasone acetate can accumulate at inflammatory sites, in mouse liver and mouse lung via nanostructured lipid carriers. Dexamethasone acetate can be used to prepare topical formulations for studies related to sensorineural hearing loss, γ-carrageenan-induced paw edema, chronic active hepatitis, pulmonary diseases, and inflammation after vitreoretinal surgery .
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5
LOC14
LOC14
0 Images
5 Cited Publications
Cat. No.: HY-100432
CAS No.: 877963-94-5
Purity:  ≥98.0%
Target:  

PDI

Research Areas:  

Neurological Disease Inflammation/Immunology

LOC14 is a potent Protein disulfide isomerase (PDI) inhibitor with EC50 and Kd values of 500 nM and 62 nM, respectively. LOC14 exhibits high stability in mouse liver microsomes and blood plasma, low intrinsic microsome clearance, and low plasma-protein binding . LOC14 inhibits PDIA3 activity, decreases intramolecular disulfide bonds and subsequent oligomerization (maturation) of HA in lung epithelial cells .
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4
MK-8245
MK-8245
0 Images
4 Cited Publications
Cat. No.: HY-13070
CAS No.: 1030612-90-8
Purity:  99.04%
Target:  

Stearoyl-CoA Desaturase (SCD)

Research Areas:  

Metabolic Disease

MK-8245 is a potent, liver-targeted stearoyl-CoA desaturase (SCD) inhibitor, with IC50s of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with antidiabetic and antidyslipidemic efficacy .
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4
MK-8245 Trifluoroacetate
MK-8245 Trifluoroacetate
0 Images
4 Cited Publications
Cat. No.: HY-13077
CAS No.: 1415559-41-9
Purity:  98.45%
Target:  

Stearoyl-CoA Desaturase (SCD)

Research Areas:  

Metabolic Disease

MK-8245 Trifluoroacetate is a potent, liver-targeted stearoyl-CoA desaturase (SCD) inhibitor, with IC50s of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with antidiabetic and antidyslipidemic efficacy .
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4
Ipafricept
Ipafricept
0 Images
4 Cited Publications
Cat. No.: HY-P99667
CAS No.: 1391727-24-4
Synonyms: OMP-54F28; FZD8-Fc

Target:  

Wnt

Research Areas:  

Cancer

Ipafricept (OMP-54F28; FZD8-Fc) is a first class recombinant fusion protein with the extracellular part of the human frizzled-8 receptor fused to a human IgG1 Fc fragment that binds Wnt ligands, which blocks Wnt signaling. Ipafricept reduces tumor growth and results in a decrease in both liver and lung metastases combined with Gemcitabine (HY-17026) in pancreatic cancer mouse models. Ipafricept shows solid tumor inhibition activity with well tolerance, such as desmoid tumor, germ cell cancer, ovarian cancer .
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4
Flavokawain C
Flavokawain C
0 Images
4 Cited Publications
Cat. No.: HY-N2445
CAS No.: 37308-75-1
Category:  

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