252 Results for "

mouse macrophage

" in MedChemExpress (MCE) Product Catalog:
Products (252)

252 Results for "mouse macrophage" in MCE Product Catalog:

155
155 Publications Verification
Cat. No.: HY-P7085
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; macrophage Colony Stimulating Factor 1; Colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan macrophage Colony-Stimulating Factor; PG-M-CSF; macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:  
Mouse
Source:  
E. coli
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91
91 Cited Publications
Cat. No.: HY-114180
CAS No.: 2262452-06-0
Purity:  99.95%
Synonyms: RU320521
Research Areas:  

Metabolic Disease

RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC50 of 0.7 μM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS) .
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70
70 Cited Publications
Cat. No.: HY-18234A
CAS No.: 103476-89-7
Leupeptin hemisulfate is a broad-spectrum protease inhibitor . By inhibiting the activation of the PTEN/PI3K/Akt/NF-κB/ERK1/2/p38 signaling pathway, Leupeptin hemisulfate significantly reduces LPS-induced NO and ROS production, mitochondrial membrane potential hyperpolarization, phagocytic activity, pro-inflammatory cytokine release, and M1 polarization in mouse peritoneal macrophages, and reverses autophagic flux impairment. It also decreases Concanavalin A (HY-P2149)-induced proliferation index of mouse splenic lymphocytes and the Th1/IL-10 and Th2/IL-10 cytokine ratios, thereby modulating innate and adaptive immune responses. Leupeptin hemisulfate inhibits blood coagulation and tumorigenesis in mouse skin. Leupeptin hemisulfate can be used in research on chronic inflammatory diseases and skin tumorigenesis .
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48
48 Cited Publications
Cat. No.: HY-P7361
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF2; Molgramostim; Colony Stimulating Factor 2; Molgramostin; GMCSF; CSF; Sargramostim; Granulocyte-macrophage Colony Stimulating Factor; GM-CSF; Granulocyte macrophage-Colony Stimulating Factor; Colony Stimulating Factor 2 (Granulocyte-macrophage); Colony-Stimulating Factor; Granulocyte-macrophage Colony-Stimulating Factor
Species:  
Mouse
Source:  
E. coli
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45
45 Cited Publications
Cat. No.: HY-P7090
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; Tumor Necrosis Factor (TNF Superfamily, Member 2); Prev. TNFA; Tumor Necrosis Factor-Alpha; TNF-Alpha; Tumor Necrotic Factor Alpha; TNFSF2; TNF Superfamily, Member 2; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF, macrophage-Derived; TNF-A; TNF, Monocyte-Derived; DIF; APC1 Protein; Cachectin; IMD127; TNLG1F; Tumor Necrosis Factor; Tumor Necrosis Factor Ligand 1F
Species:  
Mouse
Source:  
E. coli
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27
27 Cited Publications
Cat. No.: HY-N0171
CAS No.: 83-46-5
Beta-Sitosterol (purity≥80%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc .
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27
27 Cited Publications
Cat. No.: HY-N0171A
CAS No.: 83-46-5
Synonyms: β-Sitosterol (purity>98%); 22,23-Dihydrostigmasterol (purity>98%)
Beta-Sitosterol (purity>98%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc .
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18
18 Cited Publications
Cat. No.: HY-123942
CAS No.: 2170867-89-5
Purity:  98.82%
Diprovocim is a potent TLR1/TLR2 agonist. Diprovocim elicits full agonist activity in human THP-1 cells (EC50=110 pM). Diprovocim stimulates the release of TNF-α from mouse macrophages (EC50=1.3 nM). Diprovocim activates downstream MAPK and NF-κB signaling pathway. Diprovocim displays strong adjuvant activity in mice, particularly abetting cellular immune responses .
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10
10 Cited Publications
Cat. No.: HY-P7085A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; macrophage Colony Stimulating Factor 1; Colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan macrophage Colony-Stimulating Factor; PG-M-CSF; macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:  
Mouse
Source:  
CHO
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7
7 Cited Publications
Cat. No.: HY-P70553
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; macrophage Colony Stimulating Factor 1; Colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan macrophage Colony-Stimulating Factor; PG-M-CSF; macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:  
Mouse
Source:  
HEK293
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5
5 Cited Publications
Cat. No.: HY-P70263A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; macrophage Colony Stimulating Factor 1; Colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan macrophage Colony-Stimulating Factor; PG-M-CSF; macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:  
Mouse
Source:  
HEK293
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4
4 Cited Publications
Cat. No.: HY-P7361A
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CSF2; Molgramostim; Colony Stimulating Factor 2; Molgramostin; GMCSF; CSF; Sargramostim; Granulocyte-macrophage Colony Stimulating Factor; GM-CSF; Granulocyte macrophage-Colony Stimulating Factor; Colony Stimulating Factor 2 (Granulocyte-macrophage); Colo
Species:  
Mouse
Source:  
E. coli
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4
4 Cited Publications
Cat. No.: HY-P7417
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; Tumor Necrosis Factor (TNF Superfamily, Member 2); Prev. TNFA; Tumor Necrosis Factor-Alpha; TNF-Alpha; Tumor Necrotic Factor Alpha; TNFSF2; TNF Superfamily, Member 2; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF, macrophage-Derived; TNF-A;
Species:  
Mouse
Source:  
E. coli
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4
4 Cited Publications
Cat. No.: HY-P73807
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MMP9; Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase); Prev. CLG4B; macrophage Gelatinase; Matrix Metalloproteinase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase); Type V Collagenase; Matrix Metalloprot
Species:  
Mouse
Source:  
HEK293
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4
4 Cited Publications
Cat. No.: HY-P70571
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; Tumor Necrosis Factor (TNF Superfamily, Member 2); Prev. TNFA; Tumor Necrosis Factor-Alpha; TNF-Alpha; Tumor Necrotic Factor Alpha; TNFSF2; TNF Superfamily, Member 2; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF, macrophage-Derived; TNF-A;
Species:  
Mouse
Source:  
E. coli
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4
4 Cited Publications
Cat. No.: HY-P7257
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL4; Act-2; Prev. SCYA4; MIP1B; Prev. LAG1; HC21; MIP-1-Beta; Monocyte Adherence-Induced Protein 5 Alpha; AT744.1; Chemokine C-C Motif Ligand 4; Small Inducible Cytokine A4 (Homologous To mouse Mip-1b); Small-Inducible Cytokine A4; macrophage Inflammator
Species:  
Human
Source:  
E. coli
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4
4 Cited Publications
Cat. No.: HY-P7255
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL3; Tonsillar Lymphocyte LD78 Alpha Protein; Prev. SCYA3; C-C Motif Chemokine 3; MIP-1-Alpha; PAT 464.1; G0S19-1; SIS-Beta; LD78ALPHA; MIP1A; LD78; macrophage Inflammatory Protein 1 Alpha; SCI; Chemokine (C-C Motif) Ligand 3; Small Inducible Cytokine A3
Species:  
Mouse
Source:  
HEK293
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3
3 Cited Publications
Cat. No.: HY-P7069
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF2; Molgramostim; Colony Stimulating Factor 2; Molgramostin; GMCSF; CSF; Sargramostim; Granulocyte-macrophage Colony Stimulating Factor; GM-CSF; Granulocyte macrophage-Colony Stimulating Factor; Colony Stimulating Factor 2 (Granulocyte-macrophage); Colony-Stimulating Factor; Granulocyte-macrophage Colony-Stimulating Factor
Species:  
Mouse
Source:  
CHO
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3
3 Cited Publications
Cat. No.: HY-P7388
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MIF; L-Dopachrome Isomerase; Prev. GLIF; Glycosylation-Inhibiting Factor; Phenylpyruvate Tautomerase; MMIF; GIF; Epididymis Secretory Sperm Binding Protein; L-Dopachrome Tautomerase; macrophage Migration Inhibitory Factor; macrophage Migration Inhibitory
Species:  
Mouse
Source:  
E. coli
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3
3 Cited Publications
Cat. No.: HY-12700
CAS No.: 1043495-96-0
Purity:  98.75%
RO5256390 is an orally effective trace amine associated receptor 1 (TAAR1) agonist. RO5256390 exhibits pro-cognitive and antidepressant-like properties in rodent and primate models, showing similar brain activation patterns to Olanzapine (HY-14541). RO5256390 blocks compulsive overeating behavior in rats. RO5256390 can inhibit ATP (HY-B2176)-induced TNF secretion in mouse bone marrow-derived macrophages .
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