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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
mtCI Modulator 1
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "mtCI Modulator 1" in MCE Product Catalog:
Cat. No.: HY-189724
Research Areas:
mtCI Modulator 1 is an orally active and blood-brain barrier-permeable mtCI modulator. mtCI Modulator 1 reduces NADH oxidation/respiration, triggers adaptive stress signaling, activates AMPK to produce neuroprotective/antioxidant/autophagy/anti-inflammatory/mitochondrial biogenesis effects, and promotes Akt/AMPK-dependent inhibitory phosphorylation of GSK3β while reducing Tau phosphorylation. mtCI Modulator 1 prevents Aβ toxicity, increases oxidative stress resistance and NADPH/glutathione, inhibits NF-κB, induces autophagy/mitochondrial biogenesis, reduces Aβ/p-Tau in brain organoids, and improves mitochondrial reserve respiratory capacity. mtCI Modulator 1 activates AMPK-centered brain signaling in wild-type mice. mtCI Modulator 1 can be used for research on Alzheimer's disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
