Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
nanoscale
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "nanoscale" in MCE Product Catalog:
Synonyms: mPEG1000-Hydroxy; Polyethylene glycol monomethyl ether 1000
Synonyms: mPEG5000-Hydroxy; Polyethylene glycol monomethyl ether 5000
Research Areas:
m-PEG5000-OH (mPEG5000-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG1000-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery .
Cat. No.: HY-112624F1
Cat. No.: HY-172445
CAS No.: 438545-06-3
Synonyms: SS-DNA
Cat. No.: HY-140696B
CAS No.: 9004-74-4
Synonyms: mPEG550-Hydroxy; Polyethylene glycol monomethyl ether 550
Cat. No.: HY-140696H
CAS No.: 9004-74-4
Synonyms: mPEG750-Hydroxy; Polyethylene glycol monomethyl ether 750
Cat. No.: HY-140696C
CAS No.: 9004-74-4
Synonyms: mPEG20000-Hydroxy; Polyethylene glycol monomethyl ether 20000
Cat. No.: HY-152901
CAS No.: 2106868-12-4
Target:
Research Areas:
Chol-N3 is a bioorthogonal-based chol probe. Chol-N3 can combine with super-resolution fluorescence microscopy (SRM), providing direct visualization of nanoscale lipid heterogeneity in the cell surface of resting living cells . Chol-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-W1113135
CAS No.: 2828447-14-7
Target:
Research Areas:
Carboxymethyl-β-cyclodextrin sodium salt is a negatively charged β-cyclodextrin derivative, as well as a metal ion chelator and solubilizing reagent. Carboxymethyl-β-cyclodextrin sodium salt forms stable aqueous complexes with Ba 2+, Ca 2+, Cd 2+, Ni 2+, Pb 2+, Sr 2+, and Zn 2+ ions. Carboxymethyl-β-cyclodextrin sodium salt derived hydrogel carriers support oral insulin delivery via paracellular permeation across Caco-2 monolayers and produce sustained hypoglycemic effects in diabetic mice. Carboxymethyl-β-cyclodextrin sodium salt can be conjugated onto folate-modified BSA nanoparticles to boost folate receptor-mediated endocytosis, elevate intracellular anticancer drug uptake and trigger cell apoptosis. Carboxymethyl-β-cyclodextrin sodium salt can be utilized for chiral separation in capillary electrophoresis, development of nanoscale drug carriers and nucleic acid transfection research .
Cat. No.: HY-134939
CAS No.: 943022-11-5
Target:
Research Areas:
thio-Miltefosine is a modulator of rafts in membrane tissue. Rafts are nanoscale aggregates of different lipids and proteins that profoundly affect cellular function. Thio-Miltefosine modulates membrane phase behavior on cell-derived giant plasma membrane vesicles .
Cat. No.: HY-162828
STAT3/HDAC-IN-2 (compound 18) is a dual inhibitor of STAT3 and HDAC, inducing autophagy and apoptosis. STAT3/HDAC-IN-2 is an amphiphilic hydroxamic acid hybrid based on the natural product isopropanol lactone (IAL) and is a nanoscale anticancer agent. STAT3/HDAC-IN-2 can self-assemble in water to form nanoparticles, which have higher tumor tissue accumulation, cellular uptake and anticancer properties compared to the free state .
Cat. No.: HY-184613
Polydopamine nanoparticles (PDA NPs) are nanoscale materials formed by the self-polymerization of dopamine monomers under specific conditions. Their structural characteristics include a polyphenolic structure and a surface rich in functional groups such as amino and phenolic hydroxyl groups, which provide abundant chemical modification sites.
Cat. No.: HY-P12358
CAS No.: 1245010-44-9
Target:
Research Areas:
SPG-178 is a synthetic neutral Self-assembling peptide. In neutral aqueous solution, SPG-178 spontaneously assembles into an antiparallel β-sheet nanoscale three-dimensional hydrogel (SPG-178-Gel) through electrostatic and hydrophobic interactions, and biologically mimics the natural extracellular matrix (ECM) to provide a microenvironment that promotes cell proliferation and angiogenesis .
Cat. No.: HY-D3382
Target:
Research Areas:
SGC3 is a fluorescent dye with lipophilic properties. SGC3 can be used to study synaptic vesicle recycling and "kiss-and-run" exocytosis by monitoring dye efflux through nanoscale fusion pores, and its detection mechanism relies on its own lipophilic properties. SGC3 generates fluorescence when bound to lipid membranes, and a decrease in fluorescence intensity can be detected when SGC3 leaves vesicles and exists in a free state in solution .
Cat. No.: HY-P12350
CAS No.: 1261043-80-4
Target:
Research Areas:
Ac-I3K-NH2 is a surfactant-like peptide. Ac-I3K-NH2 self-assembles into β-sheet nanofibers through β-sheet hydrogen bonding, hydrophobic interactions, and electrostatic repulsion. Ac-I3K-NH2 forms ribbon-like nanofibers with nanoscale widths, adopting a β-sheet conformation, with lateral stacking driven by isoleucine side-chain contacts. Ac-I3K-NH2 templates the sol-gel condensation of tetraethoxysilane, producing silica nanotubes. Ac-I3K-NH2 templates the synthesis of one-dimensional Pt nanostructures with P7A as a capping agent .
Cat. No.: HY-W1113135A
CAS No.: 2828447-14-7
Target:
Research Areas:
Carboxymethyl-β-cyclodextrin sodium salt, for capillary electrophoresis is a negatively charged β-cyclodextrin derivative, as well as a metal ion chelator and solubilizing reagent. Carboxymethyl-β-cyclodextrin sodium salt, for capillary electrophoresis forms stable aqueous complexes with Ba 2+, Ca 2+, Cd 2+, Ni 2+, Pb 2+, Sr 2+, and Zn 2+ ions. Carboxymethyl-β-cyclodextrin sodium salt derived hydrogel carriers support oral insulin delivery via paracellular permeation across Caco-2 monolayers and produce sustained hypoglycemic effects in diabetic mice. Carboxymethyl-β-cyclodextrin sodium salt can be conjugated onto folate-modified BSA nanoparticles to boost folate receptor-mediated endocytosis, elevate intracellular anticancer drug uptake and trigger cell apoptosis. Carboxymethyl-β-cyclodextrin sodium salt can be utilized for chiral separation in capillary electrophoresis, development of nanoscale drug carriers and nucleic acid transfection research .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
