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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10035 Results for "
negative cooperativity
" in MedChemExpress (MCE) Product Catalog:
Products (10035)
10035 Results for "negative cooperativity" in MCE Product Catalog:
104
104 Publications Verification
Cat. No.: HY-K1006
MCE Penicillin-Streptomycin (100×), Sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria, which contains 10,000 units/mL of penicillin and 10 mg/mL of streptomycin.
31
Category:
Infection Microorganisms Antibiotics Animal Husbandry Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
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28 Cited Publications
Cat. No.: HY-150150
Purity: 96.40%
Target:
Research Areas:
SiRNA Negative Control is a siRNA of 21 nucleotides, and can be used as a negative control. SiRNA Negative Control has no homology to most known gene sequence. SiRNA Negative Control can be used in human, mouse and rat cells in vitro. SiRNA Negative Control can be used as experimental control benchmark, verification of experimental reliability and standardization reference. SiRNA Negative Control is a common negative control used in most research articles.
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23 Cited Publications
Cat. No.: HY-R04602
MicroRNA Mimic Negative Control is a miRNA mimic of 21-nucleotides, and can be used as a negative control. The sequence of MicroRNA Mimic Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
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16 Cited Publications
Cat. No.: HY-RI04602
MicroRNA Inhibitor Negative Control is a full-length nucleotide 2'-methoxy modified oligonucleotide, and can be used as a negative control. The sequence of MicroRNA Inhibitor Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
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11 Cited Publications
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Research Areas:
ACBI1 is a potent and cooperative SMARCA2, SMARCA4 and PBRM1 degrader with DC50s of 6, 11 and 32 nM, respectively. ACBI1 is a PROTAC degrader. ACBI1 shows anti-proliferative activity. ACBI1 induces apoptosis .
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8 Cited Publications
iMDK is a potent PI3K inhibitor and inhibits the growth factor MDK (also known as midkine or MK). iMDK suppresses non-small cell lung cancer (NSCLC) cooperatively with A MEK inhibitor without harming normal cells and mice .
8
8 Cited Publications
Cat. No.: HY-110171A
Purity: 99.37%
iMDK quarterhydrate is a potent PI3K inhibitor and inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate suppresses non-small cell lung cancer (NSCLC) cooperatively with A MEK inhibitor without harming normal cells and mice .
3
3 Cited Publications
Cat. No.: HY-RI04602A
MicroRNA Antagomir Negative Control is a chemically-modified oligonucleotide (2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification), and can be used as a negative control. The sequence of MicroRNA Antagomir Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
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3 Cited Publications
Cat. No.: HY-K1050
MCE Gentamicin, Sterile (10 mg/mL) is a filtered and sterilized antibiotic solution that can be used directly in cell culture. Gentamicin acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria, mainly for gram-negative and gram-positive bacteria.
2
1
1 Cited Publications
Cat. No.: HY-13259D
Purity: ≥98.0%
Target:
Research Areas:
MG-132 (negative control) is the negative control form of MG-132 (HY-13259) .
1
1 Cited Publications
Cat. No.: HY-R04602A
MicroRNA Agomir Negative Control is a chemically-modified double-strand miRNA mimic, and can be used as a negative control. The sequence of MicroRNA Agomir Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
1
1 Cited Publications
Cat. No.: HY-156822
Target:
Research Areas:
FAM-labeled siRNA Negative Control is a fluorescently labeled negative control in the siRNA set.
1
1 Cited Publications
Cat. No.: HY-R04602F
1
1 Cited Publications
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Research Areas:
AMG 193 is an orally active MTA-cooperative PRMT5 inhibitor with antitumor activity. AMG 193, when complexed with MTA, preferentially inhibits the growth of MTAP-deficient tumor cells by inhibiting PRMT5 (IC50=0.107 μM), thereby protecting normal cells with wild-type MTAP .
1
1 Cited Publications
Research Areas:
XL01126 is a blood-brain barrier-permeable, selective LRRK2 PROTAC degrader (DC50: 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2)). XL01126 forms a positively cooperative ternary complex with VHL E3 ubiquitin ligase and LRRK2, mediating the polyubiquitination and proteasomal degradation of LRRK2. XL01126 induces Mitophagy. XL01126 is applicable to research related to Parkinson's disease .
1
1 Cited Publications
Cat. No.: HY-RS01374
Research Areas:
BAX Human Pre-designed siRNA Set A contains three designed siRNAs for BAX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
1
1 Cited Publications
Cat. No.: HY-RS08877
Target:
Research Areas:
MYC Human Pre-designed siRNA Set A contains three designed siRNAs for MYC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
1
1 Cited Publications
Cat. No.: HY-RS17037
Target:
Research Areas:
Mavs Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mavs gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
