4 Results for "

neuritogenesis

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "neuritogenesis" in MCE Product Catalog:

Noribogaine hydrochloride
Noribogaine hydrochloride
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Cat. No.: HY-136832
CAS No.: 110514-35-7
Target:  

Serotonin Transporter Potassium Channel Arrestin Opioid Receptor

Research Areas:  

Cardiovascular Disease Neurological Disease

Noribogaine hydrochloride is an orally active, blood-brain barrier permeable SERT inhibitor (IC50=50-300 nM) and hERG channel blocker. Noribogaine hydrochloride enhances serotonergic transmission, activates the κ-opioid receptor (OPRK) G protein signaling pathway and inhibits β-arrestin recruitment. Meanwhile, Noribogaine hydrochloride blocks the μ-opioid receptor (OPRM) signaling pathway as well as ion channels associated with cardiac repolarization. Noribogaine hydrochloride induces neuritogenesis, upregulates GDNF mRNA expression, and modulates opioid tolerance. Noribogaine hydrochloride reduces alcohol-seeking behavior in experimental animals, and is widely used in studies related to depression, addiction, alcoholism, and cardiotoxicity .
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Epobis
Epobis
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Cat. No.: HY-P3585
CAS No.: 915091-83-7
Target:  

TNF Receptor

Research Areas:  

Neurological Disease Inflammation/Immunology

Epobis, a dendrimeric peptide, is a recombinant form of erythropoietin. Epobis is a potent erythropoietin receptor agonist. Epobis promotes neuritogenesis in primary motoneurons. Epobis decrease TNF release and crosses the blood-brain barrier. Epobis has anti-inflammatory and memory enhancing properties .
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Elunetirom
Elunetirom
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Cat. No.: HY-160207
CAS No.: 2156649-32-8
Synonyms: MA-JD21; ABX-002
Target:  

Drug Intermediate FAAH Thyroid Hormone Receptor

Research Areas:  

Neurological Disease

Elunetirom (MA-JD21) is an orally active, blood-brain barrier-permeable prodrug of LL-340001. Elunetirom employs fatty acid amide hydrolase (FAAH)-dependent prodrug technology to enhance the brain delivery of LL-340001, a potent thyroid hormone receptor agonist with 15-fold higher selectivity for TRβ over TRα. Elunetirom induces T3-regulated gene expression, including that of ABCD2. Elunetirom drives neuroplasticity and bioenergetic changes, and induces neurogenesis, neuritogenesis, and synaptogenesis. Elunetirom is applicable to research related to major depressive disorder and X-linked adrenoleukodystrophy .
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Gardenin A
Gardenin A
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Cat. No.: HY-N8303
CAS No.: 21187-73-5
Category:  

Rutaceae Extract Flavonoids Flavones Plants 500 - Internal Server Error | MedChemExpress

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