22 Results for "

neuron-specific

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "neuron-specific" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-103023
CAS No.: 1181083-81-7
Purity:  99.87%
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

CLP290 is an orally available activator of the neuron-specific K +-Cl - cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ (HY-13753) rats .
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2
2 Cited Publications
Cat. No.: HY-P1241
CAS No.: 412961-36-5
BAM(8-22), a proteolytically cleaved product of proenkephalin A and sensory neuron-specific receptor (SNSR) agonist, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1. BAM(8-22) induces scratching in mice in an Mrgpr-dependent manner. In addition, BAM(8-22) has an analgesic effect and can also inhibit the activation of microglia .
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1
1 Cited Publications
Cat. No.: HY-105066
CAS No.: 211439-12-2
Purity:  99.64%
Research Areas:  

Neurological Disease

Davunetide is an eight amino acid snippet derived from activity-dependent neuroprotective protein (ADNP), a neurotrophic factor that exists in the mammalian CNS. Davunetide possesses neuroprotective, neurotrophic and cognitive protective roperties. Davunetide, a microtubule-stabilizing peptide, interacts with and stabilises neuron-specific βIII-tubulin in vitro. Davunetide penetrates the blood-brain barrier and is non-toxic. Davunetide inhibits Aβ aggregation and Aβ-induced neurotoxicity .
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1
1 Cited Publications
Cat. No.: HY-P2862A
Target:  

Enolase

Research Areas:  

Neurological Disease

Neuron-specific enolase, Human (EC 4.2.1.11), an enolase, is a biomarker in traumatic brain injury (TBI), stroke and anoxic encephalopathy after cardiac arrest and acute SCI as well .
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Cat. No.: HY-108438
CAS No.: 1201916-31-5
Target:  

Microtubule/Tubulin

Research Areas:  

Neurological Disease

TCS 2210 (compound 1) is a neuronal differentiation inducer in mesenchymal stem cells (MSCs). TCS 2210 increases expression of the neuronal markers β-III tubulin and neuron-specific enolase (NSE) .
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Cat. No.: HY-115606
CAS No.: 1135304-61-8
Research Areas:  

Neurological Disease

ML007 is a selective antagonist targeting the neuron-specific potassium-chloride co-transporter 2 (KCC2) with an IC50 for KCC2 is 537 nM, while its inhibitory activity on KCC1 is extremely weak (IC50 > 50 μM). ML077 inhibits the chloride ion excretion function of KCC2, increasing the intracellular chloride ion concentration, thereby enhancing the depolarization mediated by chloride ion channels. ML007 can promote glucose-stimulated insulin secretion (GSIS) without relying on KATP channels. ML007 can be used to study the functions related to pain, epilepsy, and insulin secretion .
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Cat. No.: HY-P1241A
BAM(8-22) TFA, a proteolytically cleaved product of proenkephalin A and sensory neuron-specific receptor (SNSR) agonist, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1. BAM(8-22) TFA induces scratching in mice in an Mrgpr-dependent manner. In addition, BAM(8-22) TFA has an analgesic effect and can also inhibit the activation of microglia .
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Cat. No.: HY-P811343
Synonyms: BDR2, HPCA, neuron-specific calcium-binding protein hippocalcin, Calcium-binding protein BDR-2

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse

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Cat. No.: HY-P82256
Synonyms: STX1A; STX1; Syntaxin-1A; neuron-specific antigen HPC-1

Host:  

Rabbit

Application:  

WB, IP, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81290
Synonyms: ENO2; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; neuron-specific enolase; NSE

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81290B
Synonyms: ENO2; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; neuron-specific enolase; NSE

Host:  

Mouse

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81290A
Synonyms: ENO2; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; neuron-specific enolase; NSE

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P811267
Synonyms: NKHC1, KIF5A, Kinesin heavy chain isoform 5A, Kinesin heavy chain neuron-specific 1, neuronal kinesin heavy chain, NKHC

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81290AA
Synonyms: ENO2; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; neuron-specific enolase; NSE

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P706279
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ¹⁵N-neuron-specific enolase; ¹⁵N-γ-Enolase; ¹⁵N-Enolase 2; ¹⁵N-2-Phosphoglycerate dehydratase; ENO2; Neural Enolase; Enolase 2; HEL-S-279; NSE; Epididymis Secretory Protein Li 279; 2-Phospho-D-Glycerate Hydro-Lyase; 2-Phospho-D-Glycerate Hydrolyase; Gamma-Enolase; neuron specific Gamma Enolase; Enolase 2 (Gamma, neuronal); Phosphopyruvate Hydratase; neuronal Enriched Enolase; neurone-specific Enolase; neuron-specific Enolase; neuron specific Enolase
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P71819
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ELAVL3; ELAV Like neuron-specific RNA Binding Protein 3; ELAV Like RNA Binding Protein 3; DKFZp547J036; PLE21; Hu Antigen C; HUC; Hu-Antigen C; Paraneoplastic Cerebellar Degeneration-Associated Antigen; MGC20653; Paraneoplastic Limbic Encephalitis Antigen
Species:  
Human
Source:  
P. pastoris
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Cat. No.: HY-P72180
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ELAVL4; ELAV-Like Protein 4; Prev. HUD; ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4; PNEM; ELAV-Like Protein; ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D); Hu-Antigen D; ELAV Like neuron-specific RNA Binding P
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-103023R
CAS No.: 1181083-81-7
CLP290 (Standard) is the analytical standard of CLP290 (HY-103023). This product is intended for research and analytical applications. CLP290 is an orally available activator of the neuron-specific K+-Cl- cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ (HY-13753) rats .
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Cat. No.: HY-105066R
CAS No.: 211439-12-2
Davunetide (Standard) is the analytical standard of Davunetide (HY-105066). This product is intended for research and analytical applications. Davunetide is an eight amino acid snippet derived from activity-dependent neuroprotective protein (ADNP), a neurotrophic factor that exists in the mammalian CNS. Davunetide possesses neuroprotective, neurotrophic and cognitive protective roperties. Davunetide, a microtubule-stabilizing peptide, interacts with and stabilises neuron-specific βIII-tubulin in vitro. Davunetide penetrates the blood-brain barrier and is non-toxic. Davunetide inhibits Aβ aggregation and Aβ-induced neurotoxicity .
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Cat. No.: HY-P70271
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ENO2; Neural Enolase; Enolase 2; HEL-S-279; NSE; Epididymis Secretory Protein Li 279; 2-Phospho-D-Glycerate Hydro-Lyase; 2-Phospho-D-Glycerate Hydrolyase; Gamma-Enolase; neuron specific Gamma Enolase; Enolase 2 (Gamma, neuronal); Phosphopyruvate Hydratase
Species:  
Human
Source:  
E. coli
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