216 Results for "

neuroprotective effect

" in MedChemExpress (MCE) Product Catalog:
Products (216)

216 Results for "neuroprotective effect" in MCE Product Catalog:

76
Minocycline hydrochloride
Minocycline hydrochloride
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76 Publications Verification
Cat. No.: HY-17412
CAS No.: 13614-98-7
Target:  

Bacterial Antibiotic HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel

Research Areas:  

Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .
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76
Minocycline
Minocycline
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76 Publications Verification
Cat. No.: HY-17412A
CAS No.: 10118-90-8
Target:  

Antibiotic Bacterial HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel

Research Areas:  

Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .
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27
Donepezil Hydrochloride
Donepezil Hydrochloride
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27 Cited Publications
Cat. No.: HY-B0034
CAS No.: 120011-70-3
Synonyms: E2020
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease Cancer

Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE . Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity .
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27
Erythromycin
Erythromycin
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27 Cited Publications
Cat. No.: HY-B0220
CAS No.: 114-07-8
Category:  

Disease Research Antibacterial Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields

Target:  

Bacterial Antibiotic DNA/RNA Synthesis

Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
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27
Erythromycin lactobionate
Erythromycin lactobionate
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27 Cited Publications
Cat. No.: HY-B0220A
CAS No.: 3847-29-8
Target:  

Antibiotic Bacterial DNA/RNA Synthesis

Research Areas:  

Infection Cancer

Erythromycin lactobionate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin lactobionate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin lactobionate also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
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27
Erythromycin thiocyanate
Erythromycin thiocyanate
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27 Cited Publications
Cat. No.: HY-B0220D
CAS No.: 7704-67-8
Category:  

Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Antibacterial Anticancer Disease Research Fields

Target:  

Bacterial Antibiotic DNA/RNA Synthesis

Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin thiocyanate also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
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16
Z-LEHD-FMK
Z-LEHD-FMK
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16 Cited Publications
Cat. No.: HY-P1010
CAS No.: 210345-04-3
Target:  

Caspase Apoptosis

Research Areas:  

Neurological Disease Cancer

Z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9, protects against lethal reperfusion injury and attenuates apoptosis. Z-LEHD-FMK exhibits the neuroprotective effect in a rat model of spinal cord trauma .
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13
Stigmasterol
Stigmasterol
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13 Cited Publications
Cat. No.: HY-N0131
CAS No.: 83-48-7
Category:  

Endogenous metabolite

Target:  

MMP Endogenous Metabolite

Stigmasterol is an orally acitve, immunomodulatory agent with anti-inflammatory and neuroprotective effect, as well as able to cross the blood-brain barrier. Stigmasterol activates AMPK, which in turn inhibits NF-κB and NLRP3 signaling pathways, reduces microglia-mediated neuroinflammation, and alleviates cognitive impairment and Alzheimer's disease. Stigmasterol regulates M1/M2 polarization of microglia through the TLR4/ NF-κB pathway, thereby reducing neuropathic pain. Stigmasterol can be used for neurodegenerative diseases, inflammatory diseases, and pain management, among others .
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11
Protocatechuic acid
Protocatechuic acid
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11 Cited Publications
Cat. No.: HY-N0294
CAS No.: 99-50-3
Synonyms: 3,4-Dihydroxybenzoic acid
Category:  

Microorganisms Ketones, Aldehydes, Acids 500 - Internal Server Error | MedChemExpress

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