248

248 Publications Verification

Purity: 99.52%

Synonyms: Antibiotic AM-2282; STS; AM-2282

Category:

Infection Alkaloids Microorganisms Marine natural products Disease Research Fields Marine microorganism Indole Alkaloids

Target:

PKC PKA Apoptosis Bacterial Fungal Antibiotic

Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC₅₀s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC₅₀ of 3 μM. Staurosporine is an apoptosis inducer .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

102

Isoprenaline hydrochloride

102 Cited Publications

Cat. No.: HY-B0468

CAS No.: 51-30-9

Synonyms: Isoproterenol hydrochloride

Category:

Cardiovascular Disease Disease Research Fields Endocrinology

Target:

Adrenergic Receptor

Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

102

Isoprenaline

102 Cited Publications

Cat. No.: HY-108353

CAS No.: 7683-59-2

Target:

Adrenergic Receptor

Research Areas:

Cardiovascular Disease Endocrinology

Isoprenaline is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

102

Isoprenaline hemisulfate

102 Cited Publications

Cat. No.: HY-108353A

CAS No.: 299-95-6

Category:

Cardiovascular Disease Disease Research Fields Endocrinology

Target:

Adrenergic Receptor

Isoprenaline hemisulfate is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

90

Panobinostat lactate

90 Cited Publications

Cat. No.: HY-10224A

CAS No.: 960055-56-5

Purity: 98.67%

Synonyms: LBH589 lactate; NVP-LBH589 lactate

Target:

HDAC HIV Autophagy Apoptosis

Research Areas:

Infection Cancer

Panobinostat lactate is a potent and orally active non-selective HDAC inhibitor. Panobinostat lactate has antineoplastic activities. Panobinostat lactate effectively disrupts HIV latency. Panobinostat lactate induces cell apoptosis and autophagy. Panobinostat lactate can be used for the study of refractory or relapsed multiple myeloma .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

90

Panobinostat

90 Cited Publications

Cat. No.: HY-10224

CAS No.: 404950-80-7

Purity: 99.37%

Synonyms: LBH589; NVP-LBH589; MTX 110

Target:

HDAC Autophagy HIV Apoptosis

Research Areas:

Cancer

Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities . Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells . Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

55

Propranolol hydrochloride

55 Cited Publications

Cat. No.: HY-B0573

CAS No.: 318-98-9

Category:

Alkaloids Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields Endocrinology

Target:

Adrenergic Receptor Bacterial

Propranolol hydrochloride is a nonselective and BBB-permeableβ-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively. Propranolol hydrochloride inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

55

Propranolol

55 Cited Publications

Cat. No.: HY-B0573B

CAS No.: 525-66-6

Category:

Cardiovascular Disease Alkaloids Natural Products Neurological Disease Other Alkaloids Plants Aconitum carmichaeli Debx. Extract Disease Research Fields Ranunculaceae Extract

Target:

Adrenergic Receptor Bacterial

Propranolol is a nonselective and BBB-permeable β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively . Propranolol inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

42

Talabostat mesylate

42 Cited Publications

Cat. No.: HY-13233A

CAS No.: 150080-09-4

Purity: 98.35%

Synonyms: Val-boroPro mesylate; PT100 mesylate

Target:

Dipeptidyl Peptidase

Research Areas:

Inflammation/Immunology Cancer

Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC₅₀ < 4 nM; K_i = 0.18 nM) and the inhibitor of fibroblast activation protein (FAP) (IC₅₀ = 560 nM), inhibits DPP8/9 (IC₅₀ = 4/11 nM; K_i = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC₅₀ = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

26

Diclofenac

26 Cited Publications

Cat. No.: HY-15036

CAS No.: 15307-86-5

Purity: 99.92%

Target:

COX Apoptosis

Research Areas:

Inflammation/Immunology Cancer

Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

26

Diclofenac potassium

26 Cited Publications

Cat. No.: HY-15038

CAS No.: 15307-81-0

Purity: 99.99%

Target:

COX Apoptosis

Research Areas:

Inflammation/Immunology Cancer

Diclofenac potassium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

26

Diclofenac diethylamine

26 Cited Publications

Cat. No.: HY-15036A

CAS No.: 78213-16-8

Purity: 99.95%

Target:

COX Apoptosis

Research Areas:

Inflammation/Immunology Cancer

Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

26

Diclofenac Sodium

26 Cited Publications

Cat. No.: HY-15037

CAS No.: 15307-79-6

Purity: 99.94%

Synonyms: GP 45840

Target:

COX Apoptosis

Research Areas:

Inflammation/Immunology Cancer

Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

Compare

loading...