7 Results for "

normal breast tissue

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "normal breast tissue" in MCE Product Catalog:

Cat. No.: HY-161117
CAS No.: 1497439-74-3
Target:  

Acetyl-CoA synthetase

Research Areas:  

Cancer

AD-8007 is a blood-brain barrier-permeable ACSS2 inhibitor with human IC50 of 0.89 μM and Kd of 116.6 μM. AD-8007 reduces colony-forming ability, lipid storage levels and FASN protein expression, and induces cancer cell death. AD-8007 shrinks established tumors, acts synergistically with radiotherapy to inhibit tumor growth, reduces tumor burden, causes no obvious toxicity to normal brain tissue, and prolongs survival. AD-8007 exhibits superior metabolic stability. AD-8007 is applicable to research related to breast cancer brain metastasis .
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Cat. No.: HY-P10427
DV1 is a CXCR4 inhibitor with anti-proteolytic properties that specifically blocks the binding of SDF-1α to its receptor. DV1 inhibits the migration of breast cancer cells and enables the targeted delivery of avidin-PLGA nanoparticles to CXCR4-expressing cancer cells. DV1 not only effectively suppresses the progression of metastatic breast cancer in mouse models, but also preferentially accumulates in brain tumor tissues rather than normal brain tissues, showing potential for inhibiting intracranial tumor metastasis. As a humoral immune stimulant, DV1 induces the production of specific IgG, neutralizing antibodies and cellular immune responses, thereby providing the host with protection against lethal challenges. DV1 has been applied to studies on CXCR4-expressing cancers, glioblastoma, dengue fever and other related diseases .
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Cat. No.: HY-P10427A
Target:  

CXCR Dengue Virus

Research Areas:  

Infection

DV1 TFA is a CXCR4 inhibitor with anti-proteolytic properties that specifically blocks the binding of SDF-1α to its receptor. DV1 TFA inhibits the migration of breast cancer cells and enables the targeted delivery of avidin-PLGA nanoparticles to CXCR4-expressing cancer cells. DV1 TFA not only effectively suppresses the progression of metastatic breast cancer in mouse models, but also preferentially accumulates in brain tumor tissues rather than normal brain tissues, showing potential for inhibiting intracranial tumor metastasis. As a humoral immune stimulant, DV1 TFA induces the production of specific IgG, neutralizing antibodies and cellular immune responses, thereby providing the host with protection against lethal challenges. DV1 TFA has been applied to studies on CXCR4-expressing cancers, glioblastoma, dengue fever and other related diseases .
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Cat. No.: HY-E70727
Target:  

Haspin Kinase

Research Areas:  

Cancer

GSG2 Recombinant Human Active Protein Kinase is essential for proper chromosome congression during mitosis. The mRNA expression level of GSG2 in breast cancer tissues is much higher than that in adjacent normal tissues .
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Cat. No.: HY-189294
CAS No.: 2894038-40-3
HBT-CUR is a lysosome-targeted and polarity-responsive tumor photosensitizer. HBT-CUR generates singlet oxygen under light irradiation. HBT-CUR induces photodynamic apoptosis through oxidative stress. As a polarity-sensitive NIR fluorescent probe, HBT-CUR distinguishes tumor cells and tissues from normal ones. HBT-CUR enables tumor-specific in vivo fluorescence imaging with rapid response and long-lasting duration. HBT-CUR is used for breast cancer research .
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Cat. No.: HY-180306
CAS No.: 84693-92-5
Fluoroestradiol is an Estrogen receptor PET imaging tracer precursor. Fluoroestradiol, when radiolabeled with 18F, can be used as an Estrogen receptor PET imaging tracer. 18F-Fluoroestradiol exhibits the highest uptake selectivity and target-to-background ratio among
several 18F-labeled estrogens. 18F-Fluoroestradiol has demonstrated Estrogen receptor expression in normal brain tissues and in meningiomas. 18F-Fluoroestradiol can quantify regional Estrogen receptor expression in breast cancer. 18F-Fluoroestradiol has potential applications in assessing and monitoring heterogeneity in ovarian cancer .
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Cat. No.: HY-187170
CAS No.: 3038211-56-9
BM-51 is a selective inhibitor of CYP4Z1, with a human IC50 value of 91.7 nM. BM-51 binds to amino acid residues of CYP4Z1, thereby inhibiting its enzymatic activity. BM-51 downregulates the protein expression of stem cell markers (ALDH1A1, SOX2, OCT3/4 and KLF4) in cancer cells, inhibits cancer cell migration and invasion, and exhibits low toxicity to normal cells/tissues. BM-51 suppresses tumor initiation capacity and enhances the chemotherapeutic efficacy of Doxorubicin (HY-15142A). BM-51 can be used in breast cancer-related research .
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