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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
nucleotide binding site
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "nucleotide binding site" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: N3-Methyluridine
Target:
1
1 Cited Publications
Synonyms: 8-Bromoadenosine 5'-monophosphate; 8-Bromoadenylic acid
Research Areas:
8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is an AMP analog. 8-Bromo-AMP inhibits ADP-dependent glucokinase (ADPGK). 8-Bromo-AMP competitively inhibits ADPGK by binding to the nucleotide-binding site, inducing conformational changes, and acting on catalytic residues. 8-Bromo-AMP non-competitively inhibits rat adenylate kinase isozymes AK-M, AK II, and AK III. 8-Bromo-AMP inhibits T cell activation-induced ROS production and ROS-dependent IL-2 and IκB expression. 8-Bromo-AMP is used in research on cancer and myocardial ischemia-reperfusion injury .
Cat. No.: HY-W013706
CAS No.: 35908-31-7
Synonyms: ITP trisodium salt; Inosine triphosphate trisodium salt
Target:
Target:
Research Areas:
NCGC00188636 is a novel covalent pyruvate kinase (PYK) inhibitor. NCGC00188636 blocks nucleotide binding to the active site of pyruvate kinase. NCGC00188636 can be used for the research of the metabolism of many organisms and cell types.
Cat. No.: HY-W005824
CAS No.: 13276-52-3
Target:
2,6-Dichloropurine riboside is an antitumor and antiviral agent, which can be used for infections caused by mycoplasma. 2,6-Dichloropurine riboside also can be used to synthesize the photoaffinity probes for nucleotide binding sites in proteins .
Synonyms: 5'-p-Fluorosulfonylbenzoyladenosine
Target:
Research Areas:
FSBA (5'-p-Fluorosulfonylbenzoyladenosine) hydrochloride is a covalent modifier and affinity labeling reagent for adenine nucleotide-binding proteins. FSBA hydrochloride covalently attaches to the nucleotide-binding sites of pyruvate kinase, glutamate dehydrogenase, and p56 lck, and to a lysine residue in the ATP-binding site of cAMP-dependent protein kinase, causing loss of enzymatic activity. FSBA hydrochloride can be used for the research of T lymphoma .
Cat. No.: HY-P703337
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NLRP2; PYRIN Domain And NACHT Domain-Containing Protein 1; Prev. NALP2; NACHT, LRR And PYD Domains-Containing Protein 2; PYPAF2; PYRIN-Containing APAF1-Like Protein 2; NBS1; nucleotide-binding site Protein 1; PAN1; FLJ20510; CLR19.9; OZEMA18; nucleotide-B
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-177992
CAS No.: 1863930-80-6
Target:
Research Areas:
Cyclic-di-DAP is a base-modified analogue of c-di-AMP (HY-12326), characterized by the substitution of diaminopurine. Cyclic-di-DAP is used as a specialized tool in biochemical research to detect nucleotide-binding sites related to bacterial second messengers, RNA riboswitches, and cellular signaling pathways .
Cat. No.: HY-P703262
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CYTH2; Pleckstrin Homology, Sec7 And Coiled/Coil Domains 2 (Cytohesin-2); Prev. PSCD2; ARF nucleotide-binding site Opener; Prev. PSCD2L; ARF Exchange Factor; Cytohesin-2; Pleckstrin Homology, Sec7 And Coiled-Coil Domains 2 (Cytohesin-2), Isoform CRA_c; AR
Species:
Human
Source:
E. coli
Cat. No.: HY-122687
CAS No.: 627042-19-7
Rac1-IN-1 is a potent Rac1 inhibitor with an IC50 of 95 nM and a Ki of 6.8 μM. Rac1-IN-1 blocks the binding of Rac1 to downstream PAK1 by targeting the nucleotide-binding site of Rac1, thereby specifically inhibiting Rac1 activation without affecting Cdc42/RhoA. Rac1-IN-1 can be used for research on pancreatic cancer .
Cat. No.: HY-150172A
CAS No.: 3056945-75-3
Synonyms: ITP lithium salt; Inosine triphosphate lithium salt
Target:
Research Areas:
Inosine-5'-triphosphate (ITP) lithium salt is a nucleotide analogue that acts on multiple G proteins. Inosine-5'-triphosphate lithium salt can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Inosine-5'-triphosphate lithium salt interacts with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. Inosine-5'-triphosphate lithium salt is used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes .
Cat. No.: HY-113138R
CAS No.: 2140-69-4
Synonyms: N3-Methyluridine (Standard)
Category:
Cat. No.: HY-W013706R
CAS No.: 35908-31-7
Synonyms: ITP trisodium salt (Standard); Inosine triphosphate trisodium salt (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
