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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
nucleotide biosynthesis
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "nucleotide biosynthesis" in MCE Product Catalog:
9
9 Publications Verification
Research Areas:
GNE-140 racemate is a racemic mixture of (R)-GNE-140 (HY-100742A) and (S)-GNE-140 (HY-100742B), and also a tautomer of GNE-140 (HY-118241). GNE-140 racemate is an orally active lactate dehydrogenase inhibitor, with an IC50 of 3 nM against human LDHA and an IC50 of 5 nM against LDHB. GNE-140 racemate reduces the phosphorylation level and total protein expression of p38 MAPK, and inhibits EGF-induced AKT phosphorylation. GNE-140 racemate decreases lactate production, regulates glycolysis, the pentose phosphate pathway and nucleotide biosynthesis, increases extracellular pH, inhibits cell proliferation, migration and invasion, and induces caspase-3 activation and ROS accumulation. GNE-140 racemate can be used in research related to breast cancer, cystic fibrosis and pancreatic cancer .
5
5
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Microorganism Endogenous metabolite Disease Research Fields Cancer
Target:
5
5 Cited Publications
Cat. No.: HY-N0157A
CAS No.: 68399-76-8
Synonyms: 6-Carboxyuracil zinc; Vitamin B13 zinc
3
3 Cited Publications
Synonyms: CMP-Neu5Ac sodium salt
Target:
3
3 Cited Publications
Synonyms: Cytidine triphosphate; 5'-CTP
2
2 Cited Publications
Cat. No.: HY-N11287A
CAS No.: 108320-89-4
Target:
2
2
1
1 Cited Publications
Category:
Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
1
Research Areas:
Sulisobenzone (Benzophenone-4) is a benzophenone-type UV filter. Sulisobenzone can act as a endocrine disrupting compound. Sulisobenzone disrupts energy metabolism, nucleotide synthesis, oxidative stress response, and endocrine function. Sulisobenzone thyroid hormone biosynthesis and induces oxidative stress .
1
Category:
Natural Products Other Diseases Microorganism Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Target:
1
1 Cited Publications
Cat. No.: HY-W145649
CAS No.: 15673-79-7
Target:
Research Areas:
Ribose-5-phosphate Barium Salt is an organic compound that belongs to the monosaccharide phosphate family. It is commonly used as an intermediate in various biochemical pathways, especially in the biosynthesis of nucleotides and coenzymes. Ribose-5-phosphate Barium Salt has several applications in biochemical research, including as a precursor for the synthesis of other phosphorylated sugars and as a substrate for enzymes involved in the pentose phosphate pathway. In addition, it can be used as an energy source and dietary supplement for certain microorganisms.
Cat. No.: HY-W013046
CAS No.: 108321-05-7
Synonyms: PRPP pentasodium
Target:
Category:
Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields
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Category:
Target:
IMPDH2-IN-2 is an inhibitor of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase 2 (MtbIMPDH2) with a Ki,app value of 14 nM. IMPDH2-IN-2 blocks guanine nucleotide biosynthesis and exhibits antibacterial activity against Mycobacterium tuberculosis. IMPDH2-IN-2 can be used for research on tuberculosis .
Category:
Human Gut Microbiota Metabolites Natural Products Other Diseases Microorganism Endogenous metabolite Disease Research Fields
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
