169 Results for "

oncogenic

" in MedChemExpress (MCE) Product Catalog:
Products (169)

169 Results for "oncogenic" in MCE Product Catalog:

22
Daraxonrasib
Daraxonrasib
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22 Publications Verification
Cat. No.: HY-148439
CAS No.: 2765081-21-6
Purity:  99.68%
Synonyms: RMC-6236; RAS-IN-2
Target:  

Ras PERK

Research Areas:  

Cancer

Daraxonrasib (RMC-6236) is an orally active, non-covalent RAS (ON) inhibitor. Daraxonrasib disrupts the interaction of wild-type or mutant RAS proteins with the RAS binding domain of BRAF, with EC50 values ranging from 28-220 nM for wild-type KRAS, NRAS, HRAS, and multiple oncogenic RAS variants. Daraxonrasib inhibits pERK. Daraxonrasib has anti-tumor activity against KRAS mutant tumors .
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16
Salirasib
Salirasib
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16 Cited Publications
Cat. No.: HY-14754
CAS No.: 162520-00-5
Purity:  99.04%
Synonyms: S-Farnesylthiosalicylic acid; Farnesyl Thiosalicylic Acid; FTS
Target:  

Ras Autophagy

Research Areas:  

Cancer

Salirasib is a Ras inhibitor that inhibits specifically both oncogenically activated Ras and growth factor receptor-mediated Ras activation, resulting in the inhibition of Ras-dependent tumor growth.
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15
Deguelin
Deguelin
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15 Cited Publications
Cat. No.: HY-13425
CAS No.: 522-17-8
Purity:  99.20%
Synonyms: (-)-Deguelin; (-)-cis-Deguelin
Category:  

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