30 Results for "

p-P65

" in MedChemExpress (MCE) Product Catalog:
Products (30)

30 Results for "p-P65" in MCE Product Catalog:

3
Astegolimab
Astegolimab
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3 Cited Publications
Cat. No.: HY-P99444
CAS No.: 2173054-79-8
Synonyms: MSTT 1041A; RG 6149

Target:  

Interleukin Related MDM-2/p53 NF-κB

Research Areas:  

Cardiovascular Disease Inflammation/Immunology

Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1α, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap (NET) formation. Astegolimab is used in chronic obstructive pulmonary disease (COPD) and myocardial research .
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2
Astragaloside II
Astragaloside II
0 Images
2 Cited Publications
Cat. No.: HY-N0433
CAS No.: 84676-89-1
Synonyms: Astrasieversianin VIII
Category:  

Triterpenes Terpenoids Other Diseases 500 - Internal Server Error | MedChemExpress

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