country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

49 Results for "

p42

" in MedChemExpress (MCE) Product Catalog:

Products (49)

Sort by :

Categories

By Targets

Species:

Tags:

Sources:

Hosts:

Reactivities:

Applications:

Isotypes:

Conjugations:

Clonalities:

Modifications:

Products

Ki16425

11 Publications Verification

Cat. No.: HY-13285

CAS No.: 355025-24-0

Purity: 98.88%

Synonyms: Debio 0719

Target:

LPL Receptor YAP

Research Areas:

Neurological Disease Cancer

Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with K_is of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK . Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

ERK1/2 Antibody (YA453)

7 Cited Publications

Cat. No.: HY-P80393

Synonyms: ERK1, PRKM3, MAPK3, Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, Microtubule-associated protein 2 kinase, p44-ERK1, ERK-1, p44-MAPK, ERK2, PRKM1, PRKM2, MAPK1, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, MAP kinase isoform p42, Mitogen-activated protein kinase 2, ERK-2, p42-MAPK, MAP kinase 2, MAPK 2

Host:

Rabbit

Application:

WB, ICC/IF, IP, FC

Reactivity:

Human, Mouse, Rat

Compare

Please select quantity

August 31

Get Quote

View All Sizes

CYM5442

5 Cited Publications

Cat. No.: HY-10968

CAS No.: 1094042-01-9

Purity: 98.83%

Target:

LPL Receptor

Research Areas:

Neurological Disease

CYM5442 is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC₅₀ of 1.35 nM. CYM5442 is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 can easily penetrate the central nervous system (CNS) .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

CYM5442 hydrochloride

5 Cited Publications

Cat. No.: HY-10968A

CAS No.: 1783987-80-3

Target:

LPL Receptor

Research Areas:

Neurological Disease

CYM5442 hydrochloride is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC₅₀ of 1.35 nM. CYM5442 hydrochloride is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 hydrochloride activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 hydrochloride can easily penetrate the central nervous system (CNS) .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Olodanrigan

4 Cited Publications

Cat. No.: HY-13106

CAS No.: 1316755-16-4

Purity: 98.89%

Synonyms: EMA401; PD-126055; (S)-EMA400

Target:

Angiotensin Receptor

Research Areas:

Cardiovascular Disease Neurological Disease Endocrinology

Olodanrigan (EMA401) is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. It is under development as a neuropathic pain therapeutic agent. Olodanrigan (EMA401) analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Proinsulin C-peptide (human)

1 Cited Publications

Cat. No.: HY-P1856

CAS No.: 33017-11-7

Target:

Insulin Receptor PDGFR MAPKAPK2 (MK2)

Research Areas:

Cardiovascular Disease Metabolic Disease Inflammation/Immunology

Proinsulin C-peptide (human) is a peptide consisting of 31 amino acids that links the A and B chains of proinsulin to ensure its correct folding. Proinsulin C-peptide (human) inhibits the high glucose-induced increase in PDGF-β receptor protein expression and the phosphorylation of p42/p44 MAP kinase. Proinsulin C-peptide (human) increases the deformability of erythrocytes derived from type 1 diabetes, inhibits insulin-induced neointimal thickening, and suppresses the proliferation of rat aortic smooth muscle cells cultured under high-glucose conditions .

Compare