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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
p55PIK
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "p55PIK" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P701744
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PIK3R3; PI3-Kinase Regulatory Subunit Gamma; Phosphoinositide-3-Kinase Regulatory Subunit 3; PI3K Regulatory Subunit Gamma; Phosphatidylinositol 3-Kinase 55 KDa Regulatory Subunit Gamma; PI3-Kinase Subunit P55-Gamma; Phosphatidylinositol 3-Kinase Regulato
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P10797
Research Areas:
TAT-N24 is a cell-penetrating peptide and also an inhibitor of p55PIK. TAT-N24 disrupts the interactions between p55PIK and p53, PCNA or Rb, blocks the p53-dependent ubiquitin-mediated degradation process, and inhibits the nuclear translocation and phosphorylation of NF-κB p65. TAT-N24 enhances MMS-induced p53-dependent cell apoptosis, inhibits DNA synthesis, reduces the expression of Cyclin D1, and induces cell cycle arrest at the G0/G1 or S phase. TAT-N24 inhibits the activation of NLRP3 and NLRC4 inflammasomes, reduces the expression of ZBP1-PANoptosome components, and suppresses PANoptosis. TAT-N24 can be used in research related to leukemia, colon cancer, cervical cancer, liver cancer, corneal neovascularization, restenosis and acute glaucoma .
Cat. No.: HY-P10854
CAS No.: 2415370-74-8
Target:
Research Areas:
Cat. No.: HY-RS10538
Target:
Research Areas:
PIK3R3 Human Pre-designed siRNA Set A contains three designed siRNAs for PIK3R3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19801
Target:
Research Areas:
Pik3r3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pik3r3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
