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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
62 Results for "
parathyroid hormone (PTH)
" in MedChemExpress (MCE) Product Catalog:
Products (62)
62 Results for "parathyroid hormone (PTH)" in MCE Product Catalog:
15
15 Publications Verification
Cat. No.: HY-P0059
CAS No.: 52232-67-4
Synonyms: Human parathyroid hormone-(1-34); hPTH (1-34)
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Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
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3 Cited Publications
Cat. No.: HY-P1252
CAS No.: 12583-68-5
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2 Cited Publications
Cat. No.: HY-P1955A
CAS No.: 1334237-71-6
Synonyms: Velcalcetide hydrochloride; AMG 416 hydrochloride; KAI-4169 hydrochloride
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PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.
Cat. No.: HY-P2426
CAS No.: 118102-98-0
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Cat. No.: HY-P10277
CAS No.: 2222514-07-8
Synonyms: Transcon PTH; ACP-014
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Cat. No.: HY-P3075
CAS No.: 112540-82-6
Synonyms: pTHrP (1-34)
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PTHR PKA PKC PI3K Akt ERK NADPH Oxidase Reactive Oxygen Species (ROS) TGF-beta/Smad Caspase Apoptosis NO Synthase
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pTH-Related Protein (1-34) (human,mouse,rat) (pTHrP (1-34)) is a parathyroid hormone-related protein fragment. Binding of pTH-Related Protein (1-34) (human,mouse,rat) to PTH1R triggers cAMP/PKA and PKC signaling, PI3K-mediated Akt and ERK1/2 phosphorylation, NADPH oxidase-dependent ROS generation, and TGF-beta1 and p47phox expression. pTH-Related Protein (1-34) (human,mouse,rat) induces fibronectin upregulation, osteoblast differentiation, osteoclastic bone resorption, bone formation, eNOS/NO-mediated vasodilation, and sensitization of type II pneumocytes to ultraviolet-induced apoptosis (apoptosis) via caspase 3. pTH-Related Protein (1-34) (human,mouse,rat) can be used in research on diabetic nephropathy, breast cancer, acute lung injury, humoral hypercalcemia of malignancy, osteoporosis, and cartilage degeneration .
Cat. No.: HY-P10078
CAS No.: 90880-43-6
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Cat. No.: HY-P4697A
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Cat. No.: HY-P1418A
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Cat. No.: HY-17613R
CAS No.: 870964-67-3
Synonyms: KHK7580 (Standard)
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Evocalcet (Standard) is the analytical standard of Evocalcet. This product is intended for research and analytical applications. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
Cat. No.: HY-P1955
CAS No.: 1262780-97-1
Synonyms: Velcalcetide; AMG 416; KAI-4169
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Cat. No.: HY-P0059A
CAS No.: 99294-94-7
Synonyms: Human parathyroid hormone-(1-34) acetate hydrate; hPTH (1-34) acetate hydrate
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Teriparatide acetate hydrate (Human parathyroid hormone-(1-34) acetate hydrate) is a PTH1 receptor agonist. Teriparatide acetate hydrate (Human parathyroid hormone-(1-34) acetate hydrate) can be used for osteoporosis research .
Cat. No.: HY-P4857
CAS No.: 115695-30-2
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Cat. No.: HY-P4849
CAS No.: 206010-80-2
Cat. No.: HY-176946
CAS No.: 3106619-54-6
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PTH1R agonist 4 (Example 63) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC50 value greater than 7. PTH1R agonist 4 can be used for the study of bone diseases, such as osteoporosis .
Cat. No.: HY-131206
CAS No.: 2460353-87-9
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DS37571084 is an orally active competitive antagonist of parathyroid hormone receptor 1 (PTH1R) with an IC50 value of 0.17 μM. DS37571084 is applicable to the research of bone diseases and calcium metabolism disorders associated with primary hyperparathyroidism .
Cat. No.: HY-P4827
CAS No.: 521986-14-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
