1 Result for "

particulate proteins

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "particulate proteins" in MCE Product Catalog:

Ingenol 3,20-dibenzoate
Ingenol 3,20-dibenzoate
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Cat. No.: HY-137295
CAS No.: 59086-90-7
Purity:  99.96%
Category:  

Plant Terpenoids Diterpenoids Euphorbia esula L. Extract Disease Research Fields Inflammation/Immunology Euphorbiaceae Extract

Target:  

PKC Apoptosis

Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells .
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