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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
108 Results for "
pathogenesis
" in MedChemExpress (MCE) Product Catalog:
Products (108)
108 Results for "pathogenesis" in MCE Product Catalog:
18
18 Publications Verification
Cat. No.: HY-D1300
CAS No.: 231946-72-8
Synonyms: LysoTracker Red DND-99
13
13 Cited Publications
Cat. No.: HY-P9927A
CAS No.: 1229022-83-6
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5
5 Cited Publications
Cat. No.: HY-N2279
CAS No.: 34981-26-5
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3 Cited Publications
Cat. No.: HY-D1296
CAS No.: 220524-71-0
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2
2 Cited Publications
Synonyms: GDP disodium salt
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2 Cited Publications
Cat. No.: HY-P1362
CAS No.: 317366-82-8
Synonyms: Amyloid β Peptide (42-1)(human)
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2
2 Cited Publications
Cat. No.: HY-P990034
CAS No.: 1202526-59-7
Synonyms: MLTA3698A; RG7415; PRO283698
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Gusacitinib (ASN-002) is an orally active dual SYK/JAK kinase inhibitor with IC50 values of 5, 46, 4, 11 and 8 nM for SYK, JAK1, JAK2, JAK3 and TYK2, respectively. Gusacitinib rapidly and significantly suppressed key inflammatory pathways implicated in atopic dermatitis pathogenesis. Gusacitinib can be used in the research of chronic hand eczema and cancers such as basal cell carcinoma .
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Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
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1 Cited Publications
Cat. No.: HY-P5096
CAS No.: 1802087-77-9
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1
1 Cited Publications
Cat. No.: HY-P3908
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1
1 Cited Publications
Cat. No.: HY-P1143A
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1
1 Cited Publications
Cat. No.: HY-P1143
CAS No.: 110084-95-2
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Patamostat (E-3123) is a potent protease inhibitor. Patamostat potently inhibits trypsin, plasmin and thrombin with IC50s of 39 nM, 950 nM and 1.9 μM, respectively. Patamostat may possess suppressing effects on pathogenesis and development of acute pancreatitis .
Cat. No.: HY-DY1040
CAS No.: 231946-72-8
Solvent and concentration: DMSO: 1 mM
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Pectinase (EC 3.2.1.15) is a mixed enzymes that hydrolyze pectic substances, it mostly presents in microorganisms and higher plants. Pectinase is involved in the metabolism of the cell wall as well as in the growth of the cell, senescence, ripening of fruits, pathogenesis and abscission process .
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Dopal is a metabolite and aldehyde neurotoxin of Dopamine (HY-B0451). Dopal exhibits cytotoxicity, induces α-synuclein oligomerization and aggregation, and is closely associated with the pathogenesis of Parkinson's disease. Dopal can be used in research related to Parkinson's disease .
Cat. No.: HY-P5912
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Cat. No.: HY-Y0912
CAS No.: 94790-37-1
Synonyms: N-HBTU
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HBTU (N-HBTU) is a guanidinium-based peptide coupling reagent and immunological sensitizer. HBTU can be used in combination with bases such as DIPEA (HY-130142) to complete coupling reactions, with HOBt and TMU as by-products. HBTU is a standard reagent in automated solid-phase peptide synthesis, particularly for the Fmoc/tBu strategy, which effectively promotes coupling steps, but it is not suitable for sterically hindered amino acids or dipeptide derivatives. HBTU can induce rhinitis, dermatitis, bronchial asthma and severe allergic reactions. HBTU can be used to study the pathogenesis of allergic reactions, occupational rhinitis, allergic contact dermatitis and bronchial asthma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
