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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
62 Results for "
pentose phosphate pathways
" in MedChemExpress (MCE) Product Catalog:
Products (62)
62 Results for "pentose phosphate pathways" in MCE Product Catalog:
9
9 Publications Verification
Research Areas:
GNE-140 racemate is a racemic mixture of (R)-GNE-140 (HY-100742A) and (S)-GNE-140 (HY-100742B), and also a tautomer of GNE-140 (HY-118241). GNE-140 racemate is an orally active lactate dehydrogenase inhibitor, with an IC50 of 3 nM against human LDHA and an IC50 of 5 nM against LDHB. GNE-140 racemate reduces the phosphorylation level and total protein expression of p38 MAPK, and inhibits EGF-induced AKT phosphorylation. GNE-140 racemate decreases lactate production, regulates glycolysis, the pentose phosphate pathway and nucleotide biosynthesis, increases extracellular pH, inhibits cell proliferation, migration and invasion, and induces caspase-3 activation and ROS accumulation. GNE-140 racemate can be used in research related to breast cancer, cystic fibrosis and pancreatic cancer .
4
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Microorganism Endogenous metabolite Disease Research Fields
Target:
3
3 Cited Publications
Cat. No.: HY-W009371
CAS No.: 18265-46-8
3
3 Cited Publications
Cat. No.: HY-W009371C
CAS No.: 207671-46-3
Target:
3
3 Cited Publications
Synonyms: Adonitol; Adonite; BBP-418
Target:
3
3 Cited Publications
Target:
2
2 Cited Publications
Cat. No.: HY-W712327
CAS No.: 105931-44-0
Target:
Research Areas:
D-Xylulose 5-phosphate sodium is a pentose phosphate ester and an essential intermediate metabolite in the pentose phosphate pathway (PPP) and the non-oxidative phase of the pentose phosphate pathway. D-xylulose-5-phosphate sodium can be efficiently synthesized through the phosphorylation of D-xylulose catalyzed by D-xylulokinase (XKS1 from Saccharomyces cerevisiae), with ATP regeneration facilitated by the phosphoenolpyruvate (PEP)/pyruvate kinase (PK) system .
2
2 Cited Publications
Synonyms: (±)-Arabinose; DL-Arabinose; dl-Arabinose
1
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-W145649
CAS No.: 15673-79-7
Target:
Research Areas:
Ribose-5-phosphate Barium Salt is an organic compound that belongs to the monosaccharide phosphate family. It is commonly used as an intermediate in various biochemical pathways, especially in the biosynthesis of nucleotides and coenzymes. Ribose-5-phosphate Barium Salt has several applications in biochemical research, including as a precursor for the synthesis of other phosphorylated sugars and as a substrate for enzymes involved in the pentose phosphate pathway. In addition, it can be used as an energy source and dietary supplement for certain microorganisms.
1
1 Cited Publications
Cat. No.: HY-126876
CAS No.: 1178583-19-1
Research Areas:
GL-V9 inhibits proliferation of HepG2 cell (IC50 is 35.2 μM) through induction of apoptosis and cell cycle arrest at G2/M phase. GL-V9 regulates mitochondrial membrane potential and increases the production of intracellular reactive oxygen species. GL-V9 inhibits the pentose phosphate pathway (PPP), enhances fatty acid oxidation (FAO) through activation of AMPK, and thus inhibits the metastasis of cancer cells. GL-V9 exhibits antitumor efficacy in mouse model .
1
1 Cited Publications
Cat. No.: HY-128788A
Research Areas:
ddhCTP trisodium solution (100 mM ± 3 mM) is an endogenously produced pyrimidine base analog with a Kd of 17.0 nM for LLDH and an IC50 of 55.8 μM for GAPDH. By inhibiting key metabolic enzymes such as GAPDH, ddhCTP trisodium reduces glycolytic flux and shifts metabolic flow toward the pentose phosphate pathway, thereby regulating the redox balance of cells. As a competitive CTP analog, ddhCTP trisodium terminates RNA synthesis by flavivirus RdRps and SARS-CoV-2 RdRp, and inhibits Zika virus replication in vivo. ddhCTP trisodium can be used in studies related to viral infections, COVID-19 and Zika virus infections .
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Cat. No.: HY-W012530
CAS No.: 156-06-9
Category:
Ketones, Aldehydes, Acids Other Diseases Disease markers Endocrine diseases Nervous System Disorder Microorganism Endogenous metabolite Disease Research Fields
Target:
Target:
Cat. No.: HY-W009371A
CAS No.: 4300-28-1
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Target:
Cat. No.: HY-112537S1
Purity: ≥98.0%
Cat. No.: HY-100582R
CAS No.: 488-81-3
Synonyms: Adonitol (Standard); Adonite (Standard); BBP-418 (Standard)
Category:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
