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56 Results for "

peripheral nerve

" in MedChemExpress (MCE) Product Catalog:

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PRT062607

5 Cited Publications

Cat. No.: HY-15322

CAS No.: 1370261-96-3

Purity: 99.38%

Synonyms: P505-15; PRT-2607; BIIB-057

Target:

Syk Apoptosis Caspase

Research Areas:

Inflammation/Immunology Cancer

PRT062607 (P505-15; PRT-2607) is an orally active ATP-competitive Syk inhibitor with an IC₅₀ value of 1 nM, and exhibits at least 80-fold selectivity over other kinases. PRT062607 blocks B cell antigen receptor-mediated activation, Fcε receptor 1-mediated basophil degranulation and microglial phagocytosis, and induces caspase-dependent apoptosis and microglial death. PRT062607 inhibits tumor growth and peripheral nerve injury-induced mechanical allodynia, and prevents neuronal loss. PRT062607 can be used in research related to rheumatoid arthritis, chronic lymphocytic leukemia, non-Hodgkin's lymphoma, neurodegenerative diseases and neuropathic pain .

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August 31

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Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed)

3 Cited Publications

Cat. No.: HY-Y0850

CAS No.: 9002-89-5

Target:

Biochemical Assay Reagents

Research Areas:

Neurological Disease

Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed) is a non-biodegradable, hydrophilic, odorless biomedical polymer with cell adhesion/proliferation inhibition, peripheral nerve regeneration induction, dissolution enhancement, and non-toxic, biocompatible properties .

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