Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
peroxisomal
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "peroxisomal" in MCE Product Catalog:
3
3 Cited Publications
Target:
Research Areas:
CMPD-39 is a selective non-covalent inhibitor of the ubiquitin-specific protease USP30 (IC50=~20 nM), with high selectivity over other DUB family members (1-100 μM). CMPD-39 inhibits the deubiquitinating activity of USP30, enhances the ubiquitination of mitochondrial proteins TOMM20 and SYNJ2BP; thus, CMPD-39 promotes phosphoubuitin accumulation, thereby accelerating mitochondrial autophagy (mitophagy) and peroxisomal autophagy (pexophagy). CMPD-39 significantly restores impaired mitochondrial function in dopaminergic neurons derived from Parkinson's disease patients .
1
1
Target:
Research Areas:
Indole-3-butyric acid (Indolebutyric acid) potassium is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid potassium is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
1
1 Cited Publications
Cat. No.: HY-P70059
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ECH1; Enoyl-CoA Hydratase 1, peroxisomal; Enoyl-CoA Hydratase 1; peroxisomal Enoyl-CoA Hydratase 1; Delta(3,5)-Delta(2,4)-Dienoyl-CoA Isomerase, Mitochondrial; Epididymis Secretory Sperm Binding Protein; HPXEL; Delta3,5-Delta2,4-Dienoyl-CoA Isomerase; Del
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P73375
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRDX5; B166; Peroxiredoxin 5; Thioredoxin-Dependent Peroxiredoxin 5; AOEB166; Peroxiredoxin-5, Mitochondrial; ACR1; Alu Co-Repressor 1; PLP; Peroxiredoxin V; peroxisomal Antioxidant Enzyme; MGC142285; Liver Tissue 2D-Page Spot 71B; MGC117264; Thioredoxin
Species:
Mouse
Source:
E. coli
Cat. No.: HY-E70009
CAS No.: 61116-22-1
Synonyms: ACO
Target:
Research Areas:
Acyl-CoA oxidase (ACO) is a peroxisomal catalyst. Acyl-CoA oxidase acts as a key rate-limiting enzyme in the process of peroxisomal fatty acid β-oxidation. Acyl-CoA oxidase participates in lipid catabolism and phytohormone biosynthesis pathways .
Cat. No.: HY-141659A
Target:
Research Areas:
(R)-CMPD-39 is the R enantiomer of CMPD-39 ( HY-141659 ). CMPD-39 is a selective non-covalent inhibitor of the ubiquitin-specific protease USP30 (IC50 =~20 nM), with high selectivity over other DUB family members (1-100 μM). CMPD-39 inhibits the deubiquitinating activity of USP30, enhances the ubiquitination of mitochondrial proteins TOMM20 and SYNJ2BP; thus, CMPD-39 promotes phosphoubuitin accumulation, thereby accelerating mitochondrial autophagy (mitophagy) and peroxisomal autophagy (pexophagy). CMPD-39 significantly restores impaired mitochondrial function in dopaminergic neurons derived from Parkinson's disease patients .
Cat. No.: HY-130587
CAS No.: 57775-27-6
Synonyms: Piperazine sultosylate; A-585
Target:
Research Areas:
Sultosilic acid piperazine salt (Piperazine sultosylate; A-585) is a lipid-lowering agent. Sultosilic acid piperazine salt modifies the blood lipids levels, reduces platelet adhesiveness without promoting peroxisomal activity of hepatocytes or producing other adverse side-effects .
Cat. No.: HY-142976
CAS No.: 121842-79-3
Target:
Research Areas:
Tetranor-12(S)-HETE is the major β-oxidation product resulting from peroxisomal metabolism of 12(S)-HETE (HY-124404A) in numerous tissues. 12(S)‐HETE to tetranor‐12(S)‐HETE conversion could be a marker for psoriasis .
Cat. No.: HY-19109
CAS No.: 107813-63-8
Target:
Research Areas:
RG-7152 is a tetrazolyl-substituted leukotriene D4 receptor antagonist that can induce peroxisomal β-oxidation and peroxisome bifunctional enzymes (PBEs) in hepatocytes in various animal models. It has been shown to significantly increase PBE levels and β-oxidation activity in rat and mouse liver homogenates, while smaller effects were observed in guinea pigs and monkeys and no effect in dogs. In vitro studies have also shown that it can induce PBEs comparable to clofibric acid, indicating its potential as a peroxisome proliferator .
Cat. No.: HY-P77133
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PEX11A; MGC119947; peroxisomal Biogenesis Factor 11 Alpha; MGC138534; peroxisomal Biogenesis Factor 11A; HsPEX11p; PMP28; CDNA FLJ10553 Fis, Clone NT2RP2002325, Highly Similar To peroxisomal Membrane Protein 11A; peroxisomal Membrane Protein 11A; PEX11A P
Species:
Human
Source:
HEK293
Cat. No.: HY-B1520
CAS No.: 24818-79-9
Synonyms: Aluminum clofibrate
Aluminium clofibrate is an orally active peroxisome proliferator. Aluminium clofibrate increases peroxisomal β-oxidation enzyme activities, elevates catalase. Aluminium clofibrate can be used in the research of cancer .
Target:
Research Areas:
sEH-IN-26 is a urea structure-based soluble epoxide hydrolase (sEH) inhibitor with selectivity for mammalian cytosolic and peroxisomal sEH. sEH-IN-26 can be used for the research of inflammation and epoxide hydrolase-related diseases .
Cat. No.: HY-E71710
Target:
Research Areas:
3α,7α,12α-Trihydroxy-5β-cholest-24-enoyl-CoA hydratase (EC 4.2.1.107) forms part of the rat peroxisomal multifunctional enzyme perMFE-2, which also exhibits a dehydrogenase activity.
Cat. No.: HY-P700383
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PEX19; PXMP1; Prev. PXF; PMPI; peroxisomal Farnesylated Protein; 33 KDa Housekeeping Protein; HK33; Housekeeping Gene, 33kD; Peroxin-19; PBD12A; D1S2223E; peroxisomal Biogenesis Factor 19; PMP1
Species:
Human
Source:
E. coli
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
