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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
phosphopeptide recognition
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "phosphopeptide recognition" in MCE Product Catalog:
3
3 Cited Publications
Target:
Research Areas:
Bractoppin is a potent and selective agent-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem(t) BRCT domain (binding IC50: 74 nM). Bractoppin diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51. Bractoppin preferentially inhibits BRCA1 tBRCT-dependent steps in the DNA damage response .
Cat. No.: HY-P2480
CAS No.: 889112-06-5
Cat. No.: HY-189688
Target:
Research Areas:
tBRCT-IN-1 (Compound 12) is a BRCA1 tBRCT domain inhibitor that is expected to block the recognition of phosphopeptides by the tandem BRCT domain. tBRCT-IN-1 is predicted by computational modeling to bind to the BRCA1 tBRCT domain. tBRCT-IN-1 can be used in cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
