62 Results for "

physiological conditions

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "physiological conditions" in MCE Product Catalog:

146
BODIPY 493/503
BODIPY 493/503
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146 Publications Verification
Cat. No.: HY-W090090
CAS No.: 121207-31-6
Synonyms: Pyrromethene 546
BODIPY493/503 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
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78
Oseltamivir acid
Oseltamivir acid
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78 Cited Publications
Cat. No.: HY-13318
CAS No.: 187227-45-8
Purity:  99.50%
Synonyms: GS 4071; Ro 64-0802; Oseltamivir carboxylate
Target:  

Influenza Virus Drug Metabolite

Research Areas:  

Infection Neurological Disease

Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses. Oseltamivir acid has an extremely weak ability to penetrate the BBB under normal physiological conditions, but its blood-brain barrier penetration is significantly enhanced under inflammatory conditions .
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28
BODIPY 493/503 methyl bromide
BODIPY 493/503 methyl bromide
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28 Cited Publications
Cat. No.: HY-D1614
CAS No.: 216434-81-0
Target:  

Fluorescent Dye

Research Areas:  

Others

BODIPY493/503 methyl bromide is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
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6
BODIPY 558/568 C12
BODIPY 558/568 C12
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6 Cited Publications
Cat. No.: HY-138226
CAS No.: 158757-84-7
Purity:  98.42%
BODIPY 558/568 C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
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3
BODIPY 505/515
BODIPY 505/515
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3 Cited Publications
Cat. No.: HY-D1237
CAS No.: 21658-70-8
BODIPY505/515 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 505/515 nm .
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2
BODIPY 500/510 C1, C12
BODIPY 500/510 C1, C12
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2 Cited Publications
Cat. No.: HY-D1617
CAS No.: 144672-74-2
BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 500/510 nm . Protect from light, stored at -20°C.
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1
(D-Pro7)-Angiotensin I/II (1-7)
(D-Pro7)-Angiotensin I/II (1-7)
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1 Cited Publications
Cat. No.: HY-P1656
CAS No.: 586962-44-9
Target:  

Angiotensin Receptor Mas-related G-protein-coupled Receptor (MRGPR)

Research Areas:  

Cardiovascular Disease

(D-Pro7)-Angiotensin I/II (1-7) is a potent Mas receptor inhibitor with a Ki of 0.001 μM for rat receptors. (D-Pro7)-Angiotensin I/II (1-7) competitively blocks the binding of Angiotensin-(1-7) to the Mas receptor and attenuates the vasodilatory effect of rat aortas under physiological and hypertensive conditions. (D-Pro7)-Angiotensin I/II (1-7) can be used for studies on the function of the renin-angiotensin system and the pathological mechanisms of hypertension .
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1
iGP-1
iGP-1
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1 Cited Publications
Cat. No.: HY-121970
CAS No.: 27031-00-1
Target:  

Phosphoglycerate Dehydrogenase (PHGDH) Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase

Research Areas:  

Metabolic Disease

iGP-1 is a cell-permeable, selective mixed inhibitor of mitochondrial sn-glycerol-3-phosphate dehydrogenase (mGPDH), with IC50s of 6.3 μM and 13.6 μM for rat mGPDH activity and H2O2 production, respectively. iGP-1 specifically blocks the mitochondrial component of the glycerophosphate shuttle without affecting cytosolic GPDH. iGP-1 not only inhibits cell proliferation and glutaminolysis, and enhances glycolysis, but also significantly alters key cellular physiological processes such as apoptosis, ROS production, HIF-1α stability and mitochondrial membrane potential. iGP-1 remains active in neutrophil cultures under both normoxic and hypoxic conditions, and serves as an ideal probe for glycerol-3-phosphate metabolic mechanisms. iGP-1 has been applied to studies on prostate cancer and related metabolic pathways .
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Methotrexate metabolite
Methotrexate metabolite
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1 Cited Publications
Cat. No.: HY-108251
CAS No.: 19741-14-1
Purity:  98.44%
Synonyms: DAMPA
Target:  

Antifolate Drug Metabolite Dihydrofolate reductase (DHFR) Parasite

Research Areas:  

Infection Inflammation/Immunology

Methotrexate metabolite (DAMPA) is an active metabolite of Methotrexate. Methotrexate is a Folic acid (HY-16637) antagonist, widely used as an immunosuppressant. Methotrexate metabolite is an antimalarial agent that inhibits parasite growth under physiological folic acid conditions, with IC50 values of 446 nM and 812 nM against folic acid-sensitive strains and highly resistant strains, respectively. Methotrexate metabolite exhibits pharmacokinetic characteristics of rapid clearance and extensive metabolism, with a mean clearance rate of 1.9 l/kg/h and a mean terminal half-life of 51 minutes. Methotrexate metabolite is promising for research in the field of inflammation .
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Xylenol orange tetrasodium salt, IND
Xylenol orange tetrasodium salt, IND
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1 Cited Publications
Cat. No.: HY-W110883
CAS No.: 3618-43-7
Xylenol orange tetrasodium salt, IND is commonly used as a colorimetric indicator for metal titration and possesses Zn 2+ chelating activity. Xylenol orange tetrasodium salt, IND binds Zn 2+ under physiological pH, and its Zn-XO complex allows visual differentiation between tartrate and malate ions. Xylenol orange tetrasodium salt, IND undergoes decolorization upon oxidation by hydrogen peroxide, undergoes a Co (II)-catalyzed pseudo-second-order reaction in a strong alkaline environment, and regulates the ferrous ion oxidation process mediated by peroxy radicals. Xylenol orange tetrasodium salt, IND forms colored ternary complexes with various anions, cations and iron-alanine, which is suitable for spectrophotometric quantification and can also be used for alanine irradiation dose detection. Xylenol orange tetrasodium salt, IND is applicable to EDTA metal titration analysis under acidic conditions .
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Py-BODIPY-NHS ester
Py-BODIPY-NHS ester
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Cat. No.: HY-D1106
CAS No.: 201998-61-0
BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions . Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells .
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BODIPY 493/503 (solution)
BODIPY 493/503 (solution)
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Cat. No.: HY-DY1004
CAS No.: 121207-31-6
BODIPY 493/503 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm.
Solvent and concentration: DMSO: 5 mM.
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BODIPY FL C12
BODIPY FL C12
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Cat. No.: HY-D1570
CAS No.: 158757-79-0
BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 480/508 nm .
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HEPPSO
HEPPSO
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Cat. No.: HY-D0874
CAS No.: 68399-78-0
HEPPSO is a zwitterionic Good's buffer suitable for physiological pH conditions. HEPPSO forms high-order oligomers in aqueous solutions and can form a 1:1 complex with Cu 2+ via its hydroxyalkyl and tertiary amine groups. However, HEPPSO contains a structurally similar trace impurity lacking an alkanesulfonic acid side chain. The complex formed by this impurity and Cu 2+ has a very low Ka; therefore, HEPPSO may interfere with studies on copper speciation analysis in natural water bodies .
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Creatine-d3 hydrate
Creatine-d3 hydrate
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Cat. No.: HY-W010388AS
CAS No.: 284664-86-4
Creatine-d3 (hydrate) is a deuterium labeled Creatine hydrate. Creatine hydrate is pivotal in energy metabolism of muscle and brain cells, both in physiological and in pathological conditions .
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Oseltamivir acid-d3
Oseltamivir acid-d3
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Cat. No.: HY-13318S
CAS No.: 1242184-43-5
Purity:  ≥98.0%
Synonyms: GS 4071-d3; Ro 64-0802-d3; Oseltamivir carboxylate-d3
Oseltamivir acid-d3 is a deuterium labeled Oseltamivir acid (HY-13318). Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses. Oseltamivir acid has an extremely weak ability to penetrate the BBB under normal physiological conditions, but its blood-brain barrier penetration is significantly enhanced under inflammatory conditions .
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Cyclohexane-1,2,3,4,5,6-hexaol
Cyclohexane-1,2,3,4,5,6-hexaol
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Cat. No.: HY-W021265
CAS No.: 6917-35-7
Synonyms: Cyclohexane-1,2,3,4,5,6-hexol
Category:  

Natural Products Microorganisms Moraceae Extract Plants 500 - Internal Server Error | MedChemExpress

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