14

DEHP

14 Publications Verification

Cat. No.: HY-B1945

CAS No.: 117-81-7

Synonyms: Bis(2-ethylhexyl) phthalate; Ergoplast FDO; ESBO-D 82

Category:

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:

Environmental Pollutants Endogenous Metabolite

DEHP (Bis(2-ethylhexyl) phthalate) is a widely used plasticizer, which has orally active. DEHP can produce a wide spectrum of toxic effects on organisms including neurotoxicity, liver toxicity, immunotoxicity, and reproductive toxicity .

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12

Dibutyl phthalate

12 Cited Publications

Cat. No.: HY-Y0304

CAS No.: 84-74-2

Category:

Natural Products Plants Other Families Extract

Target:

Environmental Pollutants

Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications . May cause toxicity and adverse neurobehavioral effects .

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6

Tris(2-chloroethyl) phosphate

6 Cited Publications

Cat. No.: HY-107859

CAS No.: 115-96-8

Purity: 95.12%

Synonyms: TCEP

Target:

Environmental Pollutants FXR Calcium Channel Toll-like Receptor (TLR) SOD Reactive Oxygen Species (ROS) DNA/RNA Synthesis Interleukin Related NF-κB TNF Receptor Apoptosis

Research Areas:

Metabolic Disease

Tris(2-chloroethyl) phosphate (TCEP) is a widely used organic phosphorus flame retardant, mainly used as a plasticizer. Tris(2-chloroethyl) phosphate has orally active hepatotoxicity, inducing an increase in reactive oxygen species (ROS) and calcium ions (Ca ²⁺) influx, a decrease in mitochondrial membrane potential (△Ψm), and causing DNA damage and cell apoptosis. Tris(2-chloroethyl) phosphate directly binds to FXR, inducing obesity and the formation of fatty liver in mice. Chloroethyl) phosphate activates the TLR4/NF-κB pathway, triggering liver inflammation .

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2

Phthalic acid

2 Cited Publications

Cat. No.: HY-I0508

CAS No.: 88-99-3

Category:

Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:

Biochemical Assay Reagents Reactive Oxygen Species (ROS) Estrogen Receptor/ERR

Phthalic acid is the final common metabolite of phthalic acid esters (PAEs). Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA). Phthalic acid has applications in the preparation of phthalate ester plasticizers. Phthalic acid exhibits mutagenic effect and causes genetic damage in mammalian germ cells .

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2

Diethyl phthalate

2 Cited Publications

Cat. No.: HY-Y0284

CAS No.: 84-66-2

Target:

Environmental Pollutants Apoptosis Aminotransferases (Transaminases) Phosphatase

Research Areas:

Inflammation/Immunology Endocrinology

Diethyl phthalate is an orally active plasticizer and detergent base. Diethyl phthalate increases the activities of ACP, ALP, SDH, and ALT in liver, muscle, or both tissues. Diethyl phthalate induces dose-dependent mortality and sluggish behavior in freshwater fish. Diethyl phthalate may induce male reproductive toxicity. Diethyl phthalate is added to plastic polymers to help maintain their flexibility .

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2

2,5-Furandicarboxylic acid

2 Cited Publications

Cat. No.: HY-W002105

CAS No.: 3238-40-2

Category:

Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite Biochemical Assay Reagents

2,5-Furandicarboxylic acid is an endogenous metabolite that can be detected in human urine. 2,5-Furandicarboxylic acid serves as an environmentally friendly substitute for terephthalic acid in the production of polyesters. 2,5-Furandicarboxylic acid can be used as the raw material for various chemical intermediates to synthesize polymers, polyurethanes, thermosetting resins, and plasticizers .

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2

Dioctyl phthalate

2 Cited Publications

Cat. No.: HY-W013755

CAS No.: 117-84-0

Synonyms: DNOP; Di-n-octyl phthalate; Phthalic acid dioctyl ester

Target:

Biochemical Assay Reagents Aminotransferases (Transaminases) Phosphatase Bacterial

Research Areas:

Inflammation/Immunology

Dioctyl phthalate (DNOP) is a plasticizer. Dioctyl phthalate increases the activities of alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the liver, as well as the levels of creatinine and urea in the kidney. Exposure to Dioctyl phthalate disrupts the homeostasis of the intestinal microbial community, increases the abundance of pathogenic bacteria, and reduces the abundance of beneficial bacteria such as Lactobacillus. Dioctyl phthalate induces significant and dose-dependent inflammatory responses in the liver, spleen and kidney of mice .

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1

3-Hydroxyvaleric acid

1 Cited Publications

Cat. No.: HY-113004

CAS No.: 10237-77-1

Purity: ≥98.0%

Category:

Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite

3-Hydroxyvaleric acid is a five-carbon ketone body byproduct that can undergo an anaplerotic reaction to replenish the intermediates of the tricarboxylic acid cycle. 3-Hydroxyvaleric acid is one of the important monomers for the synthesis of polyhydroxyalkanoates (PHA). PHA is a type of biodegradable plastic that is widely used in environmentally friendly packaging, disposable products, and medical materials .

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1

Acetyl tributyl citrate

1 Cited Publications

Cat. No.: HY-W010981

CAS No.: 77-90-7

Synonyms: Tributyl O-acetylcitrate; ATBC

Target:

Environmental Pollutants Biochemical Assay Reagents

Research Areas:

Others

Acetyl tributyl citrate (Tributyl O-acetylcitrate) is a pharmaceutical excipient and biodegradable hydrophobic plasticizer. Acetyl tributyl citrate can be used in cosmetics, food packaging, and as a flavoring substance for food .

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1

DEHP (Standard)

1 Cited Publications

Cat. No.: HY-B1945R

CAS No.: 117-81-7

Synonyms: Bis(2-ethylhexyl) phthalate (Standard); Ergoplast FDO (Standard); ESBO-D 82 (Standard)

Category:

Natural Products Endogenous metabolite

Target:

Reference Standards Endogenous Metabolite

DEHP (Standard) is the analytical standard of DEHP. This product is intended for research and analytical applications. DEHP (Bis(2-ethylhexyl) phthalate) is a widely used plasticizer, which has orally active. DEHP can produce a wide spectrum of toxic effects on organisms including neurotoxicity, liver toxicity, immunotoxicity, and reproductive toxicity .

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1

Dibutyl phthalate-3,4,5,6-d4

1 Cited Publications

Cat. No.: HY-Y0304S

CAS No.: 93952-11-5

Target:

Isotope-Labeled Compounds

Research Areas:

Neurological Disease Cancer

Dibutyl phthalate-3,4,5,6-d₄ is the deuterium labeled Dibutyl phthalate. Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications . May cause toxicity and adverse neurobehavioral effects .

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1

Dimethyl phthalate

1 Cited Publications

Cat. No.: HY-N7106

CAS No.: 131-11-3

Synonyms: DMP

Category:

Natural Products Microorganisms Animals Other Diseases Plants Other Families Extract Disease Research Fields

Target:

Environmental Pollutants Biochemical Assay Reagents Apoptosis Reactive Oxygen Species (ROS)

Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

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1

Tricarballylic acid

1 Cited Publications

Cat. No.: HY-W020215

CAS No.: 99-14-9

Category:

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

Mitochondrial Metabolism Endogenous Metabolite

Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a K_i value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .

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