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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1445 Results for "
platelet degranulation
" in MedChemExpress (MCE) Product Catalog:
Products (1445)
1445 Results for "platelet degranulation" in MCE Product Catalog:
242
242 Publications Verification
Synonyms: Coleonol; Colforsin; HL 362
Category:
Terpenoids Metabolic Disease Diterpenoids Plants Disease Research Fields Inflammation/Immunology Endocrinology Labiatae Extract Pueraria montana (Lour.) Merr.
Target:
45
Category:
Human Gut Microbiota Metabolites Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
39
39 Cited Publications
Synonyms: Acetylsalicylic acid; ASA
Aspirin (Acetylsalicylic acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis .
33
33 Cited Publications
Synonyms: Clopidogrelum
Target:
Research Areas:
Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
33
33 Cited Publications
Cat. No.: HY-17459
CAS No.: 120202-66-6
Synonyms: (S)-(+)-Clopidogrel bisulfate; (S)-(+)-Clopidogrel hydrogen sulfate
Target:
Research Areas:
Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation ．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
30
30 Cited Publications
Cat. No.: HY-P7055
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; platelet-Derived Growth Factor Beta Polypeptide; PDGF2; platelet-Derived Growth Factor Subunit B; platelet-Derived Growth Factor, Beta Polypeptide (Oncogene SIS); platelet-Derived Growth
Species:
Human
Source:
E. coli
29
29 Cited Publications
Target:
Research Areas:
Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID50 of 40 nM for Calpain I in human platelets . Calpeptin is also an inhibitor of cathepsin K .
26
Research Areas:
Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well .
26
26 Cited Publications
Synonyms: Eltrombopag diethanolamine salt; SB-497115GR
Research Areas:
Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag Olamine owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag Olamine can be used for the research of cardiovascular. Eltrombopag Olamine also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag Olamine can induce apoptosis in hepatocellular carcinomab (HCC) as well .
22
22 Cited Publications
Target:
Research Areas:
IOX2, a chemical probe, is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases .
22
20
Target:
Research Areas:
Tolvaptan is a selective, competitive and orally active vasopressin receptor 2 (V2R) antagonist with an IC50 of 1.28 μM for the inhibition of arginine vasopressin (AVP)-induced platelet aggregation. Tolvaptan induces cell apoposis and affects cell cycle. Tolvaptan can be used for the research of hyponatremia .
20
20 Cited Publications
Target:
19
15
15 Cited Publications
Cat. No.: HY-N0720
CAS No.: 41060-15-5
Category:
Flavonoids Phenols Polyphenols Leguminosae Extract Psoralea corylifolia L. Plants Disease Research Fields Cancer Isoflavones
Target:
14
13
13 Cited Publications
Cat. No.: HY-P7278
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; platelet-Derived Growth Factor Beta Polypeptide; PDGF2; platelet-Derived Growth Factor Subunit B; platelet-Derived Growth Factor, Beta Polypeptide (Oncogene SIS); platelet-Derived Growth
Species:
Rat
Source:
E. coli
13
13 Cited Publications
Cat. No.: HY-P7087
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; platelet-Derived Growth Factor Beta Polypeptide; PDGF2; platelet-Derived Growth Factor Subunit B; platelet-Derived Growth Factor, Beta Polypeptide (Oncogene SIS); platelet-Derived Growth Factor B Chain; Epididymis Secretory Sperm Binding Protein; Becaplermin; PDGF, B Chain; PDGF-2; Oncogene SIS; SSV; IBGC5; platelet-Derived Growth Factor Beta Polypeptide (Simian Sarcoma Viral (V-Sis) Oncogene Homolog); C-Sis; platelet Derived Growth Factor Subunit B; Proto-Oncogene C-Sis
Species:
Mouse
Source:
E. coli
13
13 Cited Publications
Synonyms: AZD6140; AR-C 126532XX
Target:
Research Areas:
Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation.
12
12 Cited Publications
Cat. No.: HY-D0199
CAS No.: 16178-48-6
Synonyms: Adenosine diphosphate disodium; ADP disodium
Target:
-
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
