57

SM-102

57 Publications Verification

Cat. No.: HY-134541

CAS No.: 2089251-47-6

Purity: 99.97%

Target:

Liposome

Research Areas:

Infection

SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

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49

ALC-0315

49 Cited Publications

Cat. No.: HY-138170

CAS No.: 2036272-55-4

Purity: 99.81%

Target:

Liposome SARS-CoV

Research Areas:

Infection

ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .

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27

mPEG2000-DMG

27 Cited Publications

Cat. No.: HY-112764

CAS No.: 160743-62-4

Purity: 98.40%

Target:

Liposome

Research Areas:

Metabolic Disease

mPEG2000-DMG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. mPEG2000-DMG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .

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23

DSPC

23 Cited Publications

Cat. No.: HY-W040193

CAS No.: 816-94-4

Synonyms: 1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine

Target:

Liposome

Research Areas:

Others

DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

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20

DSPE-PEG 2000

20 Cited Publications

Cat. No.: HY-142979

CAS No.: 892144-24-0

Purity: 99.95%

Synonyms: (C2H4O)nC42H82NO10P

Target:

Liposome

Research Areas:

Others

DSPE-PEG 2000 is a PEG polymer containing DSPE. DSPE-PEG 2000 can be used to form micelles as nanoparticles for drug delivery .

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13

SYBR Green I Nucleic Acid Gel Stain

13 Cited Publications

Cat. No.: HY-K1004

MCE SYBR Green I Nucleic Acid Gel Stain is one of the most sensitive stains available for detecting double-stranded DNA (dsDNA) in agarose and polyacrylamide gels.

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10

N-Hydroxysuccinimide

10 Cited Publications

Cat. No.: HY-Y0623

CAS No.: 6066-82-6

Synonyms: HOSu; 1-Hydroxy-2,5-pyrrolidinedione

N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .

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9

DLin-KC2-DMA

9 Cited Publications

Cat. No.: HY-112758

CAS No.: 1190197-97-7

Purity: 99.88%

Target:

Liposome

Research Areas:

Others

DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .

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7

CKK-E12

7 Cited Publications

Cat. No.: HY-134781

CAS No.: 1432494-65-9

Purity: ≥98.0%

Target:

Liposome

Research Areas:

Others

CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,

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6

Fluorescein-5-maleimide

6 Cited Publications

Cat. No.: HY-D0098

CAS No.: 75350-46-8

Synonyms: N-(5-Fluoresceinyl)maleimide

Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .

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5

Red Nucleic Acid Gel Stain (10,000×)

5 Cited Publications

Cat. No.: HY-K1007

MCE Red Nucleic Acid Gel Stain (10,000×) is a nucleic acid stain that can be used as a safer alternative to the traditional ethidium bromide (EB) stain for detecting nucleic acids in agarose gels or polyacrylamide gels.

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