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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
polyubiquitin
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "polyubiquitin" in MCE Product Catalog:
Target:
Research Areas:
UC-764864 is a selective UBE2N inhibitor. UC-764864 covalently binds UBE2N catalytic Cys87, blocks ubiquitin-UBE2N thioester formation and polyubiquitin chain synthesis. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates, and induces cell apoptosis. UC-764864 can be used for the research of acute myeloid leukemia .
Target:
Research Areas:
Ac-Phe-NH2 is a non-competitive inhibitor of polyubiquitin chain elongation at Ki value of 8 mM by destabilizing the active trimer .
Cat. No.: HY-164951
CAS No.: 2223042-67-7
Target:
Research Areas:
C1-BCEA-Acm is a linker, that can be used for synthesis of polyubiquitin chains and ubiquitin-modified substrates .
Cat. No.: HY-P990493
Target:
Research Areas:
Cat. No.: HY-P992572
Target:
Research Areas:
Anti-Mouse 4-1BB/CD137 Antibody (17B5) is a CD137 (4-1BB/TNFRSF9)-targeting antibody .Anti-Mouse 4-1BB/CD137 Antibody (17B5) induces CD137 internalization to endosomal signaling compartments and K63-linked polyubiquitination in vivo in tumor-infiltrating lymphocytes, where endosomes costain with K63-polyubiquitin chains .Anti-Mouse 4-1BB/CD137 Antibody (17B5) can be used for the research of colon carcinoma .
Cat. No.: HY-P701839
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBC; Ubiquitin C; polyubiquitin-C; Ubiquitin C Splice Variant; UBC Protein; HMG20
Species:
Human
Source:
E. coli
Cat. No.: HY-P705992
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBC; Ubiquitin C; polyubiquitin-C; Ubiquitin C Splice Variant; UBC Protein; HMG20
Species:
Human
Source:
E. coli
Cat. No.: HY-187705
CAS No.: 305333-99-7
Target:
Research Areas:
SE486-11 is an orally active USP5 inhibitor. SE486-11 increases free polyubiquitin chains and promotes the ubiquitination and degradation of MYCN. The combination of SE486-11 with SAHA (HY-10221) synergistically induces Apoptosis. SE486-11 can be used in research related to MYCN-driven neuroblastoma .
Cat. No.: HY-P86479
Synonyms: UBB; polyubiquitin-B; UBC; polyubiquitin-C; RPS27A; UBA80; UBCEP1; Ubiquitin-40S ribosomal protein S27a; Ubiquitin carboxyl extension protein 80; UBA52; UBCEP2; Ubiquitin-60S ribosomal protein L40; CEP52; Ubiquitin A-52 residue ribosomal pr; Ubiquitin K48;
Cat. No.: HY-P87377
Synonyms: Epididymis secretory protein Li 50 antibody; FLJ25987 antibody; HEL S 50 antibody; MGC8385 antibody; polyubiquitin B antibody; RPS 27A antibody; RPS27A antibody; UBA 52 antibody; UBA 80 antibody; UBA52 antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
