118 Results for "

precursor peptide

" in MedChemExpress (MCE) Product Catalog:
Products (118)

118 Results for "precursor peptide" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-13463A
CAS No.: 677007-74-8
Purity:  99.88%
Synonyms: AKR-501 maleate; E5501 maleate; YM477 maleate
Avatrombopag (AKR-501) maleate is an orally active, non-peptide thrombopoietin receptor (TPO receptor) agonist (EC50: 3.3 nM). Avatrombopag maleate mimics the biological activity of TPO. Avatrombopag maleate increases platelet production by activating intracellular signaling systems and promotes the production of platelets and megakaryocytes from hematopoietic precursor cells. Avatrombopag maleate is a substrate for cytochrome P450 (CYP) 2C9 and CYP3A .
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3
3 Cited Publications
Cat. No.: HY-114174
CAS No.: 220701-06-4
Purity:  99.13%
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing .
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2
2 Cited Publications
Cat. No.: HY-P81160
Synonyms: Glucagon like peptide-1 receptor; GLP 1 R; GLP 1 receptor; GLP 1R; Glp1r; GLP; glp1r; Glucagon like peptide 1 receptor; RATGL1RCP; Glip; MGC138331; GLP-1-R; GLP1R_HUMAN; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R; precursor.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-W010712
CAS No.: 109425-51-6
Research Areas:  

Others

Fmoc-His(Trt)-OH is a histidine derivative with a trityl (Trt) group protecting the His side chain. Fmoc-His(Trt)-OH also has an Fmoc group protecting the α-NH2 group. Fmoc-His(Trt)-OH can be used in solid-phase peptide synthesis to prevent racemization and byproduct formation. Fmoc-His(Trt)-OH acts as a protected histidine precursor in solid-phase peptide synthesis (SPPS), participating in peptide chain construction through amide bond formation. Fmoc-His(Trt)-OH can be precisely incorporated into the target peptide sequence, ensuring correct peptide chain synthesis and reducing impurity formation. Fmoc-His(Trt)-OH is mainly used in the solid-phase synthesis research of pharmaceutical peptides and bioactive peptides, and is particularly suitable for the preparation of peptide drugs requiring precise control of histidine configuration .
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1
1 Cited Publications
Cat. No.: HY-P84648
Synonyms: Brain natriuretic peptide 32 antibody; Brain type natriuretic peptide antibody; Gamma brain natriuretic peptide antibody; Natriuretic peptide B antibody; Natriuretic peptide precursor B antibody; natriuretic peptide, brain type antibody; Natriuretic peptides B antibody; natriuretic protein antibody; NPPB antibody

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P72805
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NPPB; PreproBNP; Natriuretic peptide B; Iso-ANP; Brain Natriuretic Factor Prohormone; ProBNP; Natriuretic peptide precursor B; Brain Type Natriuretic peptide; Gamma-Brain Natriuretic peptide; Natriuretic Protein; Natriuretic peptides B; BNP
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P704352
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid precursor Protein; Amyloid-Beta precursor Protein; Testicular Tissue Protein Li 2; Amyloid precursor Protein; Beta-Amyloid peptide(1-40); Alpha-SAPP; Beta-Amyloid Pept
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-113283
CAS No.: 451-13-8
Purity:  99.46%
Homogentisic acid is an orally active, blood-brain barrier-permeable amyloidogenic compound that functions as both an amyloid component and a pigment precursor. Accumulation of homogentisic acid downregulates tight junction proteins (such as claudin-5, occludin, ZO-1) and impairs blood-brain barrier integrity. Homogentisic acid and its oxidation product benzoquinone acetic acid not only induce the aggregation and fibrosis of multiple proteins (such as Aβ1-42, α-synuclein, SAA, Transthyretin (TTR), atrial natriuretic peptide), but also trigger oxidative stress, damage to the Wnt/β-catenin pathway, and neurotoxicity, leading to ochronosis pigment deposition and synaptic dysfunction. At specific concentrations, homogentisic acid exerts no cytotoxicity or genotoxicity on human peripheral blood lymphocytes, and even counteracts the genotoxicity induced by Irinotecan (HY-16562). Homogentisic acid serves as an important tool molecule for investigating the mechanisms of diseases including ochronosis, secondary amyloidosis, Alzheimer's disease, and colorectal cancer .
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Cat. No.: HY-W007970
CAS No.: 2577-40-4
H-Phe-Phe-OH is a peptide made of two phenylalanine molecules; Phenylalanine is an essential amino acid and the precursor for the amino acid tyrosine.
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Cat. No.: HY-P2198
CAS No.: 196305-05-2
PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control .
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Cat. No.: HY-103374
CAS No.: 101246-66-6
Purity:  99.55%
Synonyms: (-)-Eseroline phenylcarbamate; (-)-Phenserine
Research Areas:  

Neurological Disease

Phenserine ((-)-Eseroline phenylcarbamate) is a derivative of Physostigmine (HY-N6608) and is a potent, noncompetitive, long-acting and selective AChE inhibitor. Phenserine reduces β-amyloid precursor protein (APP) and β-amyloid peptide (Aβ) formation. Phenserine improves cognitive performance and attenuates the progression of Alzheimer's disease .
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Cat. No.: HY-125372
CAS No.: 16348-49-5
Purity:  99.85%
Synonyms: ABAO
Research Areas:  

Others

2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n



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Cat. No.: HY-P10489
CAS No.: 374675-19-1
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

Kisspeptin-14 human is a peptide hormone encoded by the KiSS-1 gene. Kisspeptin-14 human, along with several other similar peptide hormones, is produced from a common precursor protein by cleavage by different proteases. Kisspeptin-14 human is an endogenous ligand of KISS1R. Kisspeptin-14 human has the same receptor binding efficiency and potency as full-length kisspeptin. Kisspeptin-14 human binds to its receptor GPR54 and is able to activate this G protein-coupled receptor and activate multiple intracellular signaling pathways. Kisspeptin-14 human can be used to study reproductive development and tumor metastasis .
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Cat. No.: HY-P1486
CAS No.: 104180-23-6
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

Angiotensinogen (1-14), human is a fragment of the renin substrate angiotensinogen. Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides .
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Cat. No.: HY-P2538
CAS No.: 120796-97-6
Target:  

Vasopressin Receptor

Research Areas:  

Cardiovascular Disease

Big Endothelin-1 (1-38), human is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide .
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Cat. No.: HY-P3919
CAS No.: 166546-72-1
Synonyms: Pro-ADM-153-185 (human)
Target:  

CGRP Receptor

Research Areas:  

Cardiovascular Disease

Adrenotensin (human) (Pro-ADM-153-185 (human)) is a 153-185 fragment of precursor peptide of Adrenomedullin. Adrenomedullin (ADM) is a 52-amino acid multifunctional peptide, which belongs to the CGRP superfamily of vasoactive peptide hormones .
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Cat. No.: HY-P4885
CAS No.: 161818-04-8
Synonyms: AβpE3-40
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Glp-Amyloid-β (3-40) Peptide (human) (AβpE3-40) is a minor amounts of pyroglutamate-modified Aβ isolated from from 24-month-old Amyloid precursor protein (APP) transgenic Mice .
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Cat. No.: HY-P1829A
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

Angiotensin I/II (1-6) TFA contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. The precursor angiotensinogen is cleaved by renin to form angiotensin I. Angiotensin I ishydrolyzed by angiotensin-converting enzyme (ACE) to form the biologically active angiotensin II. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy .
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Cat. No.: HY-P1894
CAS No.: 315229-44-8
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid Protein Precursor 770 (135-155) is a peptide of amyloid precursor protein isoform (APP 770). APP 770 produces Aβ40/42 .
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Cat. No.: HY-P2183A
Synonyms: proSAAS(221-242) TFA
Target:  

Inhibitory Antibodies

Research Areas:  

Neurological Disease

PEN(mouse) TFA (proSAAS(221-242) TFA) is the precursor of a number of peptides that function as neuropeptides .
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