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18 Results for "

procaspases 3

" in MedChemExpress (MCE) Product Catalog:

Products (18)

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Arg-Gly-Asp-Ser

11 Publications Verification

Cat. No.: HY-12290

CAS No.: 91037-65-9

Purity: 99.93%

Synonyms: RGDS peptide; Fibronectin tetrapeptide

Target:

Integrin

Research Areas:

Inflammation/Immunology

Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.

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RGD peptide (GRGDNP)

11 Publications Verification

Cat. No.: HY-P1740

CAS No.: 114681-65-1

Target:

Integrin Apoptosis Caspase

Research Areas:

Inflammation/Immunology

RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) plays an important role in cell adhesion, migration, growth, and differentiation .

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RGD peptide (GRGDNP) TFA

11 Publications Verification

Cat. No.: HY-P1740A

Target:

Integrin Apoptosis

Research Areas:

Inflammation/Immunology Cancer

RGD peptide (GRGDNP) TFA is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) TFA competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) TFA promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) TFA plays an important role in cell adhesion, migration, growth, and differentiation .

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PAC-1

8 Cited Publications

Cat. No.: HY-13523

CAS No.: 315183-21-2

Purity: 99.93%

Synonyms: Procaspase activating compound 1

Target:

Caspase Autophagy Apoptosis

Research Areas:

Cancer

PAC-1 is a procaspase-3 activator that induces apoptosis in cancer cells with an EC₅₀ of 2.08 μM.

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Procaspase-3/6 activator 1

Cat. No.: HY-10131

CAS No.: 1100353-03-4

Purity: 98.97%

Target:

Caspase

Research Areas:

Others

Procaspase-3/6 activator 1 (compound 1541) is a highly specific and robust activator of executioner procaspases-3 and -6, with EC₅₀ values of 2.4 ± 0.2 and 2.8 ± 0.3 μM, respectively. Procaspase-3/6 activator 1 does not activate procaspases-1 or -7 .

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