20277 Results for "

protein

" in MedChemExpress (MCE) Product Catalog:

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2156

Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)

2156 Publications Verification

Cat. No.: HY-K0010

MCE Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) is a blend of 6 pan-protease inhibitors for protection of protein integrity.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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August 31

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1510

Rapamycin

1510 Cited Publications

Cat. No.: HY-10219

CAS No.: 53123-88-9

Purity: 99.94%

Synonyms: Sirolimus; AY-22989; NSC 226080

Category:

Microorganisms Macrolide Antibiotics Anti-inflammation/Immunoregulatory Anti-aging Antibiotics Disease Research Disease Research Fields Cancer

Target:

mTOR FKBP Molecular Glues Fungal Autophagy Endogenous Metabolite Antibiotic Bacterial

Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .

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1474

Protein A/G Magnetic Beads

1474 Cited Publications

Cat. No.: HY-K0202

MCE Protein A/G Magnetic Beads provide a fast and convenient method for Immunoprecipitation, Co-Immunoprecipitation and Chromatin Immunoprecipitation. The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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952

Bafilomycin A1

952 Cited Publications

Cat. No.: HY-100558

CAS No.: 88899-55-2

Purity: 99.95%

Synonyms: BafA1

Category:

Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Anticancer Disease Research Fields

Target:

Proton Pump Autophagy Antibiotic Bacterial Apoptosis

Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H ⁺-ATPase (V-ATPase) with IC₅₀ values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis .

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