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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
531 Results for "
proto-oncogene
" in MedChemExpress (MCE) Product Catalog:
Products (531)
531 Results for "proto-oncogene" in MCE Product Catalog:
92
92 Publications Verification
Cat. No.: HY-50878A
CAS No.: 1415560-69-8
Synonyms: PF-02341066 hydrochloride
Research Areas:
Crizotinib hydrochloride (PF-02341066 hydrochloride) is an orally bioavailable, selective, and ATP-competitive dual ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib hydrochloride (PF-02341066 hydrochloride) inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. It is also a ROS proto-oncogene 1 (ROS1) inhibitor. Crizotinib hydrochloride (PF-02341066 hydrochloride) has effective tumor growth inhibition .
36
36 Cited Publications
Synonyms: RR82 hydrochloride
Research Areas:
Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells .
27
27 Cited Publications
Cat. No.: HY-N6732
CAS No.: 99533-80-9
Synonyms: SF2370; Antibiotic K 252a; Antibiotic SF 2370
Target:
13
13 Cited Publications
Cat. No.: HY-P7087
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; Platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; Platelet-Derived Growth Factor Beta Polypeptide; PDGF2; Platelet-Derived Growth Factor Subunit B; Platelet-Derived Growth Factor, Beta Polypeptide (oncogene SIS); Platelet-Derived Growth Factor B Chain; Epididymis Secretory Sperm Binding Protein; Becaplermin; PDGF, B Chain; PDGF-2; oncogene SIS; SSV; IBGC5; Platelet-Derived Growth Factor Beta Polypeptide (Simian Sarcoma Viral (V-Sis) oncogene Homolog); C-Sis; Platelet Derived Growth Factor Subunit B; proto-oncogene C-Sis
Species:
Mouse
Source:
E. coli
8
5
4
4 Cited Publications
Cat. No.: HY-P80276
Synonyms: AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; MGC99656 antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody;
3
2
2
2
2
2
2 Cited Publications
Cat. No.: HY-P72948
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS proto-oncogene; McDonough Feline Sarcoma Viral (V-Fms) oncogene Homolog; BANDDOS; Macrophage Colony-Stimulating Factor 1 Receptor; CSF-1-R; proto-oncogene C-Fms; HDLS1; CSF-1 Receptor; FIM2; CD115 Antigen; GPSC; M-CSF-R; HDLS; Colony Stimulating Factor 1 Receptor; Platelet-Derived Growth Factor Receptor-Like Protein
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P700065AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF3; Heparin-Binding Growth Factor 3; Prev. INT2; proto-oncogene Int-2; HBGF-3; oncogene INT2; Fibroblast Growth Factor 3 (Murine Mammary Tumor Virus Integration Site (V-Int-2) oncogene Homolog); FGF-3; V-INT2 Murine Mammary Tumor Virus Integration Site
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P7055B
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; Platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; Platelet-Derived Growth Factor Beta Polypeptide; PDGF2; Platelet-Derived Growth Factor Subunit B; Platelet-Derived Growth Factor, Beta Polypeptide (oncogene SIS); Platelet-Derived Growth Factor B Chain; Epididymis Secretory Sperm Binding Protein; Becaplermin; PDGF, B Chain; PDGF-2; oncogene SIS; SSV; IBGC5; Platelet-Derived Growth Factor Beta Polypeptide (Simian Sarcoma Viral (V-Sis) oncogene Homolog); C-Sis; Platelet Derived Growth Factor Subunit B; proto-oncogene C-Sis
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P73094
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral oncogene Homolog 2 (Neuro/Glioblastoma Derived oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral oncogene Homolog 2, Neuro/Glioblastoma Derived oncogene Homolog; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2 Isoform C; Receptor Tyrosine-Protein Kinase ErbB-2; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; proto-oncogene C-ErbB-2; Neuroblastoma/Glioblastoma Derived oncogene Homolog; proto-oncogene Neu; Receptor Tyrosine-Protein Kinase ErbB-2 Variant; P185(ErbB2); Truncated HER2 Splice Variant P100; C-ERB-2; Receptor Protein-Tyrosine Kinase; C-ERB2; Metastatic Lymph Node Gene 19; MLN-19; Alternative Protein ERBB2; HER-2; C-Erb B2/Neu Protein; CD340; CD340 Antigen; V-Erb-B2 Avian Erythroblastic Leukemia Viral oncogene Homolog 2; HER-2/Neu; Tyrosine Kinase-Type Cell Surface Receptor HER2; Herstatin; Neuro/Glioblastoma Derived oncogene Homolog; VSCN2; Human Epidermal Growth Factor Receptor 2; MLN19; Metastatic Lymph Node Gene 19 Protein; TKR1; Erb-B2 Receptor Tyrosine Kinase 2; MLN 19
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P73486
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: YES1; YES proto-oncogene 1; Src Family Tyrosine Kinase; HsT441; C-Yes; Yes; V-Yes-1 Yamaguchi Sarcoma Viral oncogene Homolog 1; Tyrosine-Protein Kinase Yes; proto-oncogene C-Yes; YES1 proto-oncogene; Src Family Tyrosine Kinase; proto-oncogene Tyrosine-Pro
Species:
Human
Source:
Sf9 insect cells
1
1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
