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66 Results for "

rA1

" in MedChemExpress (MCE) Product Catalog:

Products (66)

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IL-17A antagonist 1

3 Cited Publications

Cat. No.: HY-101913

CAS No.: 2205034-18-8

Purity: 99.74%

Target:

Interleukin Related

Research Areas:

Inflammation/Immunology Cancer

IL-17A antagonist 1 is an interleukin-17A (IL-17A) antagonist with an IC₅₀ of 1.14 μM and a K_d of 0.66 μM. IL-17A antagonist 1 binds specifically and exclusively to the IL-17A homodimer at its central dimer interface pocket, induces a large conformational change that widens the pocket, and disrupts the IL-17A/IL-17RA interaction. IL-17A antagonist 1 does not bind to IL-17F or IL-17RA .

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Bucillamine

2 Cited Publications

Cat. No.: HY-118530

CAS No.: 65002-17-7

Purity: 98.87%

Synonyms: SA96; Thiobutarit

Target:

VEGFR

Research Areas:

Cardiovascular Disease Inflammation/Immunology

Bucillamine (SA96) is an orally active and potent sulfhydryl donor and antioxidant. Bucillamine is also an antirheumatic agent with antiangiogenic properties. Bucillamine can protect against Ischemia/reperfusion (I/R) injury in high-risk organ transplants. Bucillamine inhibits the production of VEGF. Bucillamine can be used for the research of choroidal neovascularization (CNV) and rheumatoid arthritis (RA) .

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CCP peptide TFA

1 Cited Publications

Cat. No.: HY-P2171A

Target:

Inhibitory Antibodies

Research Areas:

Inflammation/Immunology

CCP peptide TFA is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide TFA functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA) .

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GDC-0834

1 Cited Publications

Cat. No.: HY-15427

CAS No.: 1133432-49-1

Purity: 98.05%

Target:

Btk

Research Areas:

Inflammation/Immunology Cancer

GDC-0834 is an orally active selective, potent, and reversible BTK inhibitor with an IC₅₀ of 5.9 nM. GDC-0834 demonstrates pBTK-Tyr223 inhibition in mice and rats. GDC-0834 can be used for research of rheumatoid arthritis (RA) .

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Elsilimomab

1 Cited Publications

Cat. No.: HY-P99287

CAS No.: 468715-71-1

Synonyms: B-E8; Anti-IL-6 MAB B-E8

Elsilimomab (B-E8) is a IgG1 monoclonal antibody against interleukin-6 (IL-6), with a K_D of 22 pM and an IC₅₀ of 1.4 nM. Elsilimomab can be used for the research of multiple myeloma, renal cell carcinoma, and rheumatoid arthritis (RA) .

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IL-22R alpha 1 Protein, Mouse (HEK293, Fc)

1 Cited Publications

Cat. No.: HY-P77969

Purity: ≥ 95%, as determined by Bis-Tris PAGE.

Synonyms: IL22rA1; Interleukin 22 Receptor, Alpha 1; Prev. IL22R; IL-22R-Alpha-1; CRF2-9; IL-22rA1; Interleukin-22 Receptor Subunit Alpha-1; ZcytoR11; Cytokine Receptor Class-II Member 9; Interleukin 22 Receptor; Cytokine Receptor Family 2 Member 9; IL22R1; Interle

Species:

Mouse

Source:

HEK293

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