2 Results for "

rabbit cell lines

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "rabbit cell lines" in MCE Product Catalog:

Cat. No.: HY-117133
CAS No.: 1621332-91-9
Synonyms: SF0166
Target:  

Integrin

Research Areas:  

Metabolic Disease

Nesvategrast (SF0166) is a potent and selective αvβ3 antagonist with IC50 values of 0.6 nM, 8 nM, and 13 nM for αvβ3, αvβ6, and αvβ8, respectively. Nesvategrast inhibits cellular adhesion to vitronectin across human, rat, rabbit, and dog cell lines with IC50 values of 7.6 pM to 76 nM. Nesvategrast decreases neovascularization in the oxygen-induced retinopathy mouse model .
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Cat. No.: HY-122224
CAS No.: 1590379-85-3
Target:  

Sigma Receptor

Research Areas:  

Cancer

SW43 is a Sigma-2 selective ligand and agonist. SW43 is an ideal molecule for the development of cancer-targeted drug compounds. SW43 conjugated with DOX-L-NETA ( 89Y) exhibits antitumor activity in a VX2 cancer liver tumor allograft rabbit model. SW 43 conjugated with SW IV-52s to form SW III-123 activates the NF-κB pathway, has potent cytotoxicity against ovarian cancer cell lines, and induces apoptosis .
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