30 Results for "

radical cation

" in MedChemExpress (MCE) Product Catalog:
Products (30)

30 Results for "radical cation" in MCE Product Catalog:

7
Famotidine
Famotidine
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7 Publications Verification
Cat. No.: HY-B0377
CAS No.: 76824-35-6
Synonyms: MK-208
Target:  

Histamine Receptor MMP Toll-like Receptor (TLR) ERK

Research Areas:  

Infection Metabolic Disease Inflammation/Immunology

Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
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5
Inulin
Inulin
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5 Cited Publications
Cat. No.: HY-N7075
CAS No.: 9005-80-5
Category:  

Human Gut Microbiota Metabolites Polysaccharides Metabolic Disease Plants 500 - Internal Server Error | MedChemExpress

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