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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
rat bile
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "rat bile" in MCE Product Catalog:
6
6 Cited Publications
Cat. No.: HY-N0430A
CAS No.: 1198398-71-8
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Cat. No.: HY-B2119
CAS No.: 41945-48-6
Synonyms: Tauroglycocholic acid sodium salt
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Sodium tauroglycocholate (Tauroglycocholic acid sodium salt) is a multifunctional surfactant and penetration enhancer that can serve as a cholegraphic contrast agent. In organic solvents, Sodium tauroglycocholate embeds and stabilizes invertase by forming reverse micelles, and prolongs its active lifespan. In terms of transdermal absorption, Sodium tauroglycocholate effectively regulates the flux of aminophylline through snake slough by binding to keratin filaments, disrupting keratinocytes and altering lipid components of the stratum corneum. It exhibits rapid penetration characteristics without lag time at a concentration of 100 μg/mL. Sodium tauroglycocholate does not interfere with the hepatic uptake of Gd-EOB-DTPA by the bile acid transport system in rat hepatocytes .
Cat. No.: HY-17011
CAS No.: 77175-51-0
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Croconazole is an antifungal agent containing imidazole rings. Croconazole has a unique structural feature of aryl vinyl at the imidazole ring N-1. Croconazole can be used for the identification and quantitative study of major metabolites in rat urine and bile .
Cat. No.: HY-120396
CAS No.: 141318-62-9
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LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection .
Cat. No.: HY-W008125S
Synonyms: Methyl acetobromo-α-D-glucuronate-13C6 methyl ester
Cat. No.: HY-130301
CAS No.: 142974-51-4
Synonyms: S 0960
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Gallensre (S 0960) is an apical sodium-dependent bile acid transporter inhibitor (IC50 = 5.8 μmol/L). Gallensre inhibits bile salt reabsorption in a rat model. Gallensre can be used to study metabolic diseases such as bile acid cycling .
Cat. No.: HY-182255
CAS No.: 217187-87-6
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ED-594 is the glucuronide form of NB-506. ED-594 is one of the major metabolites of NB-506 in rat bile, mouse liver microsomes, rat liver microsomes and human liver microsomes .
Cat. No.: HY-N18490
CAS No.: 53939-19-8
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Saccharolactone is a potent orally active β-glucuronidase inhibitor. Saccharolactone markedly lowers biliary endogenous β-glucuronidase activity in the rat bile. Saccharolactone can stabilize glucuronide metabolites in vitro. Saccharolactone is also a strong inhibitor of CYP1A2, 2D6, 3A4 and 2C8 isoforms (IC50 < 4 mM) .
Cat. No.: HY-187039
CAS No.: 1426129-91-0
7-Glc-kaempferol 3-(6-cglc)-(1-2)-rhamnoside is a flavonol glycoside that can be found in Ginkgo biloba leaves. 7-Glc-kaempferol 3-(6-cglc)-(1-2)-rhamnoside is present in GBE50 extract, and is detected in rat bile (but not plasma) after oral administration of GBE50 extract to rats .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
